MYO1D and STARD3

		MYO1D	STARD3
Description		myosin ID	StAR related lipid transfer domain containing 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Early Endosome Plasma Membrane Microvillus Brush Border Cell Cortex Actin Cytoskeleton Basolateral Plasma Membrane Myosin Complex Axon Dendrite Axolemma Cytoplasmic Vesicle Cell Projection Neuron Projection Neuronal Cell Body Perikaryon Myelin Sheath Extracellular Exosome Apical Dendrite	Nucleoplasm Cytoplasm Mitochondrion Lysosomal Membrane Endosome Late Endosome Endoplasmic Reticulum Membrane Cytosol Membrane Late Endosome Membrane Organelle Membrane Contact Site Endoplasmic Reticulum-endosome Membrane Contact Site
	Molecular Function	Microfilament Motor Activity Nucleotide Binding Cytoskeletal Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding Protein Domain Specific Binding Calcium-dependent Protein Binding Actin Filament Binding	Protein Binding Lipid Binding Cholesterol Binding Protein Homodimerization Activity Cholesterol Transfer Activity
	Biological Process	Endocytosis Actin Filament Organization Protein Transport Actin Filament-based Movement Cellular Localization Early Endosome To Recycling Endosome Transport	Lipid Metabolic Process Progesterone Biosynthetic Process Mitochondrial Transport Lipid Transport Steroid Metabolic Process Cholesterol Metabolic Process Cholesterol Transport Small Molecule Metabolic Process Vesicle Tethering To Endoplasmic Reticulum
Pathways			Pregnenolone biosynthesis
Drugs
Diseases
GWAS		Anorexia nervosa ( 29155802) Emotional recognition ( 32366958) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Hypertension risk in short sleep duration ( 22322875) Immature fraction of reticulocytes ( 32888494 27863252) Local histogram emphysema pattern ( 25006744) Myopia ( 27182965) Neurofibrillary tangles ( 25188341) Pancreatic cancer ( 20686608) Red cell distribution width ( 32888494 27863252) Refractive error ( 32231278 23396134) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Alcohol consumption ( 31358974) Apolipoprotein A1 levels ( 32203549) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) HDL cholesterol ( 20686565 24097068) HDL cholesterol levels ( 32203549 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Hemoglobin levels ( 32327693) Menopause (age at onset) ( 26414677) Pancreatic ductal adenocarcinoma ( 30541042) Refractive error ( 32231278) Smoking behaviour (cigarettes smoked per day) ( 30679032) Triglyceride levels ( 30108155) Ulcerative colitis ( 20228799)
Interacting Genes		6 interacting genes: AATF H19 PTEN RPL37 STARD3 TFIP11	14 interacting genes: AQP6 CASC3 CLEC11A CREB3 DAPK1 GOPC LMNA MOSPD2 MYO1D RNF170 SCGB1A1 SLC39A7 VAPA VAPB
Entrez ID		4642	10948
HPRD ID		07581	06132
Ensembl ID		ENSG00000176658	ENSG00000131748
Uniprot IDs		J3KRL0 J3QRN6 K7EIG7 O94832 Q8N618	Q14849
PDB IDs			1EM2 5I9J 6TQR 6TQU
Enriched GO Terms of Interacting Partners?		Locomotor Rhythm Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Cellular Response To Electrical Stimulus Ubiquitin Ligase Activator Activity Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Spindle Assembly Involved In Female Meiosis Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Negative Regulation Of Peptidyl-serine Phosphorylation Regulation Of Synaptic Vesicle Clustering Postsynaptic Specialization Assembly Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Neuron-neuron Synaptic Transmission Phosphatidylinositol Phosphate Phosphatase Activity Central Nervous System Myelin Maintenance Negative Regulation Of Cell Size Presynaptic Membrane Organization Schmidt-Lanterman Incisure Rhythmic Synaptic Transmission Anaphase-promoting Complex Binding Postsynaptic Density Assembly Forebrain Morphogenesis Negative Regulation Of Excitatory Postsynaptic Potential Presynaptic Membrane Assembly Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity MDM2/MDM4 Family Protein Binding Ubiquitin Ligase Inhibitor Activity Vesicle Tethering To Endoplasmic Reticulum Endoplasmic Reticulum-endosome Membrane Contact Site Organelle Membrane Contact Site C21-steroid Hormone Biosynthetic Process Progesterone Biosynthetic Process Spliceosomal Complex Disassembly Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Protection From Non-homologous End Joining At Telomere U2-type Post-mRNA Release Spliceosomal Complex Embryonic Cleavage Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Leucine Zipper Domain Binding Phosphatidylinositol-3-phosphate Phosphatase Activity Prepulse Inhibition Maternal Behavior Progesterone Metabolic Process Telomere Maintenance In Response To DNA Damage Negative Regulation Of Glycoprotein Biosynthetic Process Lipid Binding Meiotic Spindle Assembly Synapse Maturation	FFAT Motif Binding COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Endoplasmic Reticulum Localization Host-mediated Activation Of Viral Genome Replication Host-mediated Perturbation Of Viral Genome Replication Host-mediated Suppression Of Viral Genome Replication Endoplasmic Reticulum Membrane Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Positive Regulation Of Monocyte Chemotaxis Intracellular Transport Viral Release From Host Cell Viral Process Endoplasmic Reticulum Exit Site Regulation Of Monocyte Chemotaxis Vesicle Budding From Membrane Protein-membrane Adaptor Activity Host-mediated Activation Of Viral Process Nitrate Transmembrane Transporter Activity DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Cellular Localization Establishment Of Localization In Cell Polychlorinated Biphenyl Binding Endoplasmic Reticulum Positive Regulation Of Deacetylase Activity Negative Regulation Of Anion Channel Activity Endoplasmic Reticulum Organization Nuclear Membrane Cholesterol Transport Endoplasmic Reticulum Unfolded Protein Response Golgi Vesicle Transport PH-gated Chloride Channel Activity Nitrate Transmembrane Transport DNA Double-strand Break Attachment To Nuclear Envelope Structural Constituent Of Nuclear Lamina Negative Regulation By Virus Of Viral Protein Levels In Host Cell Host-mediated Perturbation Of Viral Process Sterol Transport Organelle Localization By Membrane Tethering Regulation Of Monoatomic Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Response To Unfolded Protein Membrane Docking Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Mononuclear Cell Migration Regulation Of NMDA Receptor Activity Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Response To Ozone Response To Silicon Dioxide
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