MICOS10 and MPC2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MICOS10	MPC2
Description		mitochondrial contact site and cristae organizing system subunit 10	mitochondrial pyruvate carrier 2
Image		No pdb structure
GO Annotations	Cellular Component	SAM Complex Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Crista Junction MICOS Complex MIB Complex	Nucleus Mitochondrion Mitochondrial Inner Membrane Membrane Inner Mitochondrial Membrane Protein Complex
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Pyruvate Transmembrane Transporter Activity
	Biological Process	Inner Mitochondrial Membrane Organization Cristae Formation	Pyruvate Decarboxylation To Acetyl-CoA Pyruvate Import Into Mitochondria Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Pathways		Cristae formation	Pyruvate metabolism
Drugs
Diseases
GWAS
Interacting Genes		4 interacting genes: APOC2 APOC4 CIDEB MPC2	12 interacting genes: APOC1 CIDEB DIABLO MICOS10 NEAT1 RHBDD2 RPLP1 SNX1 SPG21 SYT16 TEX44 TIMM17B
Entrez ID		440574	25874
HPRD ID		18824	08525
Ensembl ID		ENSG00000173436	ENSG00000143158
Uniprot IDs		A0A087WU07 Q5TGZ0	O95563
PDB IDs			8YW6 8YW8 8YW9 9KNW 9KNX 9KNY 9MNW 9MNX 9MNY 9MNZ 9MO0
Enriched GO Terms of Interacting Partners?		Acylglycerol Homeostasis High-density Lipoprotein Particle Lipid Transport Very-low-density Lipoprotein Particle Triglyceride Homeostasis Regulation Of Triglyceride Metabolic Process Lipid Storage Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling Pyruvate Import Into Mitochondria Lipid Homeostasis Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Chylomicron Remodeling Positive Regulation Of Phospholipid Catabolic Process Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Intermediate-density Lipoprotein Particle Lipoprotein Lipase Activator Activity Pyruvate Transmembrane Transport Pyruvate Transmembrane Transporter Activity Inner Mitochondrial Membrane Protein Complex Lipid Droplet Fusion Spherical High-density Lipoprotein Particle Positive Regulation Of Triglyceride Catabolic Process Regulation Of Phospholipid Catabolic Process Lipase Inhibitor Activity Very-low-density Lipoprotein Particle Remodeling High-density Lipoprotein Particle Clearance Pyruvate Transport Import Into The Mitochondrion Pyruvate Decarboxylation To Acetyl-CoA Regulation Of Lipid Metabolic Process Triglyceride-rich Lipoprotein Particle Remodeling Phospholipase Activator Activity Very-low-density Lipoprotein Particle Assembly Lipoprotein Catabolic Process Chylomicron Phospholipid Efflux Lipid Transfer Activity Acetyl-CoA Biosynthetic Process COPI-coated Vesicle Low-density Lipoprotein Particle COPII Vesicle Coat Reverse Cholesterol Transport Identical Protein Binding Negative Regulation Of Lipoprotein Particle Clearance COPII-coated Vesicle Cargo Loading Phospholipase Binding Negative Regulation Of Cholesterol Transport Mitochondrial Transmembrane Transport Positive Regulation Of Triglyceride Metabolic Process	Very-low-density Lipoprotein Particle Assembly Protein-lipid Complex Assembly Plasma Lipoprotein Particle Assembly Regulation Of Triglyceride Metabolic Process Negative Regulation Of Phosphatidylcholine Catabolic Process
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