MPP3 and ARL2BP

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		MPP3	ARL2BP
Description		MAGUK p55 scaffold protein 3	ARF like GTPase 2 binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Adherens Junction Membrane Apical Plasma Membrane Anchoring Junction	Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix Centrosome Spindle Cytosol Cytoskeleton Cilium Midbody Ciliary Basal Body Cell Projection
	Molecular Function	Protein Binding PDZ Domain Binding	Transcription Coactivator Activity Protein Binding GTPase Regulator Activity
	Biological Process		Signal Transduction Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of DNA-templated Transcription Maintenance Of Protein Location In Nucleus
Pathways			Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane
Drugs
Diseases
GWAS		HDL cholesterol levels ( 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglyceride levels in current drinkers ( 30698716) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535) Triglycerides ( 24097068)	Mean corpuscular hemoglobin concentration ( 29403010)
Interacting Genes		38 interacting genes: APP ARL2BP BTBD1 CADM1 CCDC137 CRABP1 ERBIN EZR FAM171B FBXO7 GNG7 HAP1 HSH2D IDUA INSM1 KBTBD4 KRTAP10-3 L3MBTL2 LIN7A MCM2 MDH1 NOA1 PKNOX1 PLK2 RAB31 RPS2 RRAGC SCN2A SF3B3 SNTG2 SRPK2 TBK1 TIRAP TMEM37 TRAF2 TRIM41 ZNF655 ZPR1	8 interacting genes: ARL2 ARL3 CAMK2D CFAP20 DDX10 FLT1 MPP3 RAC1
Entrez ID		4356	23568
HPRD ID		03069	09808
Ensembl ID		ENSG00000161647	ENSG00000102931
Uniprot IDs		D3DX46 Q13368	Q9Y2Y0
PDB IDs			2K9A 3DOE 3DOF
Enriched GO Terms of Interacting Partners?			Nucleotide Binding Regulation Of Microtubule-based Process Regulation Of Microtubule Polymerization GTPase Activity Positive Regulation Of Microtubule Polymerization Ciliary Basal Body GTP Binding Cell Projection Assembly Plasma Membrane Bounded Cell Projection Assembly Regulation Of Neuronal Synaptic Plasticity Placental Growth Factor Receptor Activity Vascular Endothelial Growth Factor Receptor-1 Signaling Pathway GDP Binding Positive Regulation Of Protein Polymerization Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of Ovarian Follicle Development Negative Regulation Of Interleukin-23 Production Regulation Of ERK5 Cascade Angiotensin-activated Signaling Pathway Involved In Heart Process Embryonic Olfactory Bulb Interneuron Precursor Migration Cerebral Cortex GABAergic Interneuron Development Rho GDP-dissociation Inhibitor Binding Regulation Of Cell Adhesion Involved In Heart Morphogenesis Positive Regulation Of Supramolecular Fiber Organization Regulation Of Microtubule Cytoskeleton Organization Regulation Of Phosphorus Metabolic Process Positive Regulation Of Cell-substrate Adhesion Cytoskeleton Cilium Neuron Development Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcium- And Calmodulin-dependent Protein Kinase Complex Regulation Of Relaxation Of Cardiac Muscle Regulation Of Protein Localization To Membrane Anterior Head Development Hyaloid Vascular Plexus Regression Positive Regulation Of Locomotion Positive Regulation Of Cell Motility Regulation Of Ovarian Follicle Development Auditory Receptor Cell Morphogenesis Erythrocyte Enucleation Engulfment Of Apoptotic Cell Tangential Migration From The Subventricular Zone To The Olfactory Bulb Protein Polyglutamylation Cell-cell Junction Organization Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Cytoskeleton Organization Protein Localization To Ciliary Membrane Sodium Channel Inhibitor Activity Regulation Of Synaptic Plasticity
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