ARL2BP and ARL2

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		ARL2BP	ARL2
Description		ARF like GTPase 2 binding protein	ARF like GTPase 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix Centrosome Spindle Cytosol Cytoskeleton Cilium Midbody Ciliary Basal Body Cell Projection	Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Mitochondrial Intermembrane Space Mitochondrial Matrix Centrosome Cytosol Cytoskeleton Cilium Microtubule Cytoskeleton Lateral Plasma Membrane Ciliary Basal Body
	Molecular Function	Transcription Coactivator Activity Protein Binding GTPase Regulator Activity	Nucleotide Binding GTPase Activity Protein Binding GTP Binding GDP Binding
	Biological Process	Signal Transduction Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Positive Regulation Of DNA-templated Transcription Maintenance Of Protein Location In Nucleus	Regulation Of Glycolytic Process Protein Folding Centrosome Cycle Positive Regulation Of Cell-substrate Adhesion Regulation Of Microtubule Polymerization Positive Regulation Of Microtubule Polymerization Negative Regulation Of GTPase Activity Maintenance Of Protein Location In Nucleus Bicellular Tight Junction Assembly Regulation Of Aerobic Respiration
Pathways		Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	Post-chaperonin tubulin folding pathway Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane RAS processing
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin concentration ( 29403010)
Interacting Genes		8 interacting genes: ARL2 ARL3 CAMK2D CFAP20 DDX10 FLT1 MPP3 RAC1	8 interacting genes: ARL2BP LHX4 PDE6D POLA2 TBCD TBL1X TBL1XR1 UNC119
Entrez ID		23568	402
HPRD ID		09808	11869
Ensembl ID		ENSG00000102931	ENSG00000213465
Uniprot IDs		Q9Y2Y0	P36404
PDB IDs		2K9A 3DOE 3DOF	3DOE 3DOF
Enriched GO Terms of Interacting Partners?		Nucleotide Binding Regulation Of Microtubule-based Process Regulation Of Microtubule Polymerization GTPase Activity Positive Regulation Of Microtubule Polymerization Ciliary Basal Body GTP Binding Cell Projection Assembly Plasma Membrane Bounded Cell Projection Assembly Regulation Of Neuronal Synaptic Plasticity Placental Growth Factor Receptor Activity Vascular Endothelial Growth Factor Receptor-1 Signaling Pathway GDP Binding Positive Regulation Of Protein Polymerization Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of Ovarian Follicle Development Negative Regulation Of Interleukin-23 Production Regulation Of ERK5 Cascade Angiotensin-activated Signaling Pathway Involved In Heart Process Embryonic Olfactory Bulb Interneuron Precursor Migration Cerebral Cortex GABAergic Interneuron Development Rho GDP-dissociation Inhibitor Binding Regulation Of Cell Adhesion Involved In Heart Morphogenesis Positive Regulation Of Supramolecular Fiber Organization Regulation Of Microtubule Cytoskeleton Organization Regulation Of Phosphorus Metabolic Process Positive Regulation Of Cell-substrate Adhesion Cytoskeleton Cilium Neuron Development Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcium- And Calmodulin-dependent Protein Kinase Complex Regulation Of Relaxation Of Cardiac Muscle Regulation Of Protein Localization To Membrane Anterior Head Development Hyaloid Vascular Plexus Regression Positive Regulation Of Locomotion Positive Regulation Of Cell Motility Regulation Of Ovarian Follicle Development Auditory Receptor Cell Morphogenesis Erythrocyte Enucleation Engulfment Of Apoptotic Cell Tangential Migration From The Subventricular Zone To The Olfactory Bulb Protein Polyglutamylation Cell-cell Junction Organization Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Cytoskeleton Organization Protein Localization To Ciliary Membrane Sodium Channel Inhibitor Activity Regulation Of Synaptic Plasticity	Transcription Repressor Complex Histone Deacetylase Complex Positive Regulation Of Peptidyl-tyrosine Phosphorylation Sensory Perception Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Caveolin-mediated Endocytosis Regulation Of Peptidyl-tyrosine Phosphorylation Medial Motor Column Neuron Differentiation
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