ADAM11 and STC2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ADAM11	STC2
Description		ADAM metallopeptidase domain 11	stanniocalcin 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Axon Extracellular Matrix Presynaptic Membrane Cell Projection Perikaryon Synapse	Extracellular Region Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Golgi Apparatus Perinuclear Region Of Cytoplasm
	Molecular Function	Metalloendopeptidase Activity Integrin Binding Metallopeptidase Activity	Hormone Activity Enzyme Binding Heme Binding Protein Homodimerization Activity
	Biological Process	Proteolysis Integrin-mediated Signaling Pathway Multicellular Organismal Response To Stress Establishment Of Protein Localization Behavioral Response To Acetic Acid Induced Pain Behavioral Response To Formalin Induced Pain	Intracellular Calcium Ion Homeostasis Response To Oxidative Stress Embryo Implantation Negative Regulation Of Gene Expression Endoplasmic Reticulum Unfolded Protein Response Response To Vitamin D Response To Endoplasmic Reticulum Stress Negative Regulation Of Multicellular Organism Growth Response To Peptide Hormone Decidualization Regulation Of Hormone Biosynthetic Process Calcium Ion Homeostasis Cellular Response To Hypoxia Regulation Of Store-operated Calcium Entry
Pathways		LGI-ADAM interactions	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)	A body shape index ( 34021172) Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Appendicular lean mass ( 33097823) Atrial fibrillation ( 29892015) Birth weight ( 31043758) Height ( 25429064 31562340) Hip circumference adjusted for BMI ( 34021172) Immunoglobulin A vasculitis ( 28698626) Prostate cancer ( 23535732) Retinitis pigmentosa ( 33514863) Urate levels in overweight individuals ( 25811787) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		1 interacting genes: STC2	20 interacting genes: ADAM11 AIFM1 ARHGEF40 ARRB2 CARHSP1 CELF6 CPN1 EIF2B3 ELOB ERGIC1 FAF2 FGFR4 HK3 PEBP1 PLA2G5 POLR2C POLR3F PPP1R8 PTN RNF44
Entrez ID		4185	8614
HPRD ID		01114	04717
Ensembl ID		ENSG00000073670	ENSG00000113739
Uniprot IDs		B4DKD2 O75078	O76061 Q6FHC9
PDB IDs			7Y5Q 8A7D 8A7E 8HGH
Enriched GO Terms of Interacting Partners?		Decidualization Regulation Of Hormone Biosynthetic Process Response To Vitamin D Negative Regulation Of Multicellular Organism Growth Regulation Of Store-operated Calcium Entry Regulation Of Hormone Metabolic Process Embryo Implantation Endoplasmic Reticulum Unfolded Protein Response Regulation Of Multicellular Organism Growth Response To Vitamin Negative Regulation Of Developmental Growth
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