STC2 and AIFM1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		STC2	AIFM1
Description		stanniocalcin 2	apoptosis inducing factor mitochondria associated 1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Golgi Apparatus Perinuclear Region Of Cytoplasm	Nucleus Cytoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Cytosol Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Hormone Activity Enzyme Binding Heme Binding Protein Homodimerization Activity	DNA Binding NADH Dehydrogenase Activity Protein Binding NAD(P)H Oxidase H2O2-forming Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On NAD(P)H Protein Dimerization Activity FAD Binding Poly-ADP-D-ribose Binding
	Biological Process	Intracellular Calcium Ion Homeostasis Response To Oxidative Stress Embryo Implantation Negative Regulation Of Gene Expression Endoplasmic Reticulum Unfolded Protein Response Response To Vitamin D Response To Endoplasmic Reticulum Stress Negative Regulation Of Multicellular Organism Growth Response To Peptide Hormone Decidualization Regulation Of Hormone Biosynthetic Process Calcium Ion Homeostasis Cellular Response To Hypoxia Regulation Of Store-operated Calcium Entry	Response To Ischemia Apoptotic Process Response To Toxic Substance Neuron Differentiation Mitochondrial Respiratory Chain Complex Assembly Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Neuron Apoptotic Process Protein Import Into Mitochondrial Intermembrane Space Positive Regulation Of Necroptotic Process Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cellular Response To Hydrogen Peroxide Cellular Response To Estradiol Stimulus Cellular Response To Hypoxia Cellular Response To Nitric Oxide Mitochondrial Disulfide Relay System Response To L-glutamate Cellular Response To Aldosterone
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs			Flavin adenine dinucleotide MCC
Diseases			Combined oxidative phosphorylation deficiency (COXPD)
GWAS		A body shape index ( 34021172) Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Appendicular lean mass ( 33097823) Atrial fibrillation ( 29892015) Birth weight ( 31043758) Height ( 25429064 31562340) Hip circumference adjusted for BMI ( 34021172) Immunoglobulin A vasculitis ( 28698626) Prostate cancer ( 23535732) Retinitis pigmentosa ( 33514863) Urate levels in overweight individuals ( 25811787) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Bipolar disorder ( 31043756)
Interacting Genes		20 interacting genes: ADAM11 AIFM1 ARHGEF40 ARRB2 CARHSP1 CELF6 CPN1 EIF2B3 ELOB ERGIC1 FAF2 FGFR4 HK3 PEBP1 PLA2G5 POLR2C POLR3F PPP1R8 PTN RNF44	12 interacting genes: CASP3 DCAF7 EIF3G HSPA1A HSPA1B MLH1 NOA1 SETDB1 STC2 TSC22D4 WWC1 XIAP
Entrez ID		8614	9131
HPRD ID		04717	02161
Ensembl ID		ENSG00000113739	ENSG00000156709
Uniprot IDs		O76061 Q6FHC9	E9PMA0 O95831
PDB IDs		7Y5Q 8A7D 8A7E 8HGH	1M6I 4BUR 4BV6 4FDC 4LII 5FMH 5FS6 5FS7 5FS8 5FS9 5KVH 5KVI 8D3E 8D3G 8D3H 8D3I 8D3J 8D3K 8D3N 8D3O 8VGY
Enriched GO Terms of Interacting Partners?			Regulation Of Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Gene Expression C3HC4-type RING Finger Domain Binding ATP-dependent Protein Disaggregase Activity Positive Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Cellular Heat Acclimation Negative Regulation Of Metabolic Process Negative Regulation Of Growth Positive Regulation Of Microtubule Nucleation Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway Negative Regulation Of Inclusion Body Assembly Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Inclusion Body Perinuclear Region Of Cytoplasm Regulation Of Microtubule Nucleation Response To Oxidative Stress MRNA Catabolic Process Regulation Of Inclusion Body Assembly Regulation Of Mitotic Spindle Assembly Response To Lipid Execution Phase Of Apoptosis Enzyme Binding Protein Refolding Positive Regulation Of Defense Response Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Erythrocyte Differentiation Aggresome Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand ATP-dependent Protein Folding Chaperone Positive Regulation Of Microtubule Polymerization Regulation Of Spindle Assembly Regulation Of Protein Ubiquitination RNA Catabolic Process Cellular Response To Stress Regulation Of Mitotic Spindle Organization Response To Steroid Hormone Macromolecule Catabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Erythrocyte Differentiation Regulation Of Post-translational Protein Modification Cellular Response To Heat Regulation Of Growth Intracellular Signal Transduction Response To Hormone Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment
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