MCCD1 and RIPPLY1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MCCD1	RIPPLY1
Description		mitochondrial coiled-coil domain 1	ripply transcriptional repressor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion	Nucleus
	Molecular Function	Protein Binding	Protein Binding
	Biological Process		Negative Regulation Of Transcription By RNA Polymerase II Somite Specification Embryonic Pattern Specification Somite Rostral/caudal Axis Specification Negative Regulation Of DNA-templated Transcription
Pathways
Drugs
Diseases
GWAS		AIDS progression ( 19115949) Asthma ( 29273806 31619474) Asthma (childhood onset) ( 31619474) Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Cervical cancer ( 28806749) Inflammatory bowel disease ( 28067908) Lymphocyte count ( 32888494) Malaria ( 31844061) Ulcerative colitis ( 28067908)	Alcoholic chronic pancreatitis ( 28754779) Pancreatitis ( 23143602)
Interacting Genes		26 interacting genes: BEX3 BFSP2 CAB39 COX5B FNDC3B KANK2 KRT26 KYNU LMO4 LSM1 MEIS2 MGAT5B MKRN3 MX1 MYL7 P4HA3 PIH1D2 PPP1R16A PRR35 QARS1 RIPPLY1 USHBP1 USP20 ZNF417 ZNF587 ZNF765	44 interacting genes: AVPI1 BEND7 CFAP58 CTNNA3 DCAF15 DIRAS2 FHL2 GRAPL GRHL3 H3-4 HAND2 HDAC7 IRAK1BP1 KRT34 MCCD1 MDFI MED19 MEOX2 NDUFB7 PATZ1 PBX4 PFDN5 PLAGL2 PRR20A PRR20B PRR20C PRR20D PRR20E PTTG2 RBPMS REL RHOH RNF144B SAPCD1 THAP1 TRAF1 TRAF2 TRAF3 USP6 VAC14 VGLL1 ZMYND12 ZNF620 ZNF784
Entrez ID		401250	92129
HPRD ID		17470
Ensembl ID		ENSG00000204511	ENSG00000147223
Uniprot IDs		A0A1U9X802 P59942	Q0D2K3
PDB IDs
Enriched GO Terms of Interacting Partners?			Signaling Adaptor Activity Thioesterase Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Tumor Necrosis Factor Receptor Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Canonical NF-kappaB Signal Transduction Sequence-specific DNA Binding CD40 Receptor Complex Tumor Necrosis Factor-mediated Signaling Pathway
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