WASH2P and SNAP23

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		WASH2P	SNAP23
Description		WASP family homolog 2, pseudogene	synaptosome associated protein 23
Image		No pdb structure
GO Annotations	Cellular Component		Nucleoplasm Cytoplasm Mitochondrion Plasma Membrane Adherens Junction Focal Adhesion Cilium Membrane Phagocytic Vesicle Membrane SNARE Complex Cytoplasmic Vesicle Specific Granule Membrane Specific Granule Azurophil Granule Neuron Projection Synapse Extracellular Exosome Tertiary Granule Membrane Presynapse
	Molecular Function		SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process		Histamine Secretion By Mast Cell Exocytosis Post-Golgi Vesicle-mediated Transport Vesicle Targeting Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Membrane Fusion
Pathways			ER-Phagosome pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane trans-Golgi Network Vesicle Budding Neutrophil degranulation RHOA GTPase cycle RHOB GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RAC3 GTPase cycle RHOF GTPase cycle
Drugs
Diseases
GWAS			Bipolar disorder ( 31043756)
Interacting Genes		5 interacting genes: APP PLEKHA5 SNAP23 STAT5A TNFRSF21	33 interacting genes: ABI2 ABI3 CFTR FXR2 ITSN1 KIF5B MATR3 NAPA NAPB PRKCA SCAMP1 SCAMP2 SCARB1 SCGN SNAPIN SNTG1 STX11 STX12 STX1A STX1B STX3 STX4 STX5 STX6 STXBP2 STXBP5 TLK1 VAMP1 VAMP2 VAMP3 VAMP7 VAMP8 WASH2P
Entrez ID		375260	8773
HPRD ID		17562	03962
Ensembl ID		ENSG00000310523	ENSG00000092531
Uniprot IDs			A8K287 O00161
PDB IDs			1NHL 3ZUS
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Apoptotic Process Growth Cone Lamellipodium Positive Regulation Of Mitotic Cell Cycle Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Positive Regulation Of Inflammatory Response Regulation Of Cell Activation Regulation Of Response To Calcium Ion Cell Recognition Axon Midline Choice Point Recognition Regulation Of Multicellular Organism Growth Amylin Binding Endosome To Plasma Membrane Transport Vesicle Programmed Cell Death Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Response To Peptide Neuron Recognition Response To Cytokine Lipoprotein Particle Growth Factor Receptor Binding Main Axon Regulation Of Cytokine Production Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Regulation Of Nervous System Process Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Mast Cell Differentiation Regulation Of T Cell Proliferation Negative Regulation Of Cell-cell Adhesion Development Of Secondary Female Sexual Characteristics Negative Regulation Of Lymphocyte Activation Regulation Of B Cell Activation Negative Regulation Of Mast Cell Apoptotic Process Negative Regulation Of Leukocyte Activation Positive Regulation Of Mast Cell Differentiation Positive Regulation Of Mast Cell Proliferation Negative Regulation Of T Cell Activation	SNARE Complex SNAP Receptor Activity Vesicle Fusion Organelle Membrane Fusion Membrane Fusion Organelle Fusion SNARE Binding Exocytosis Organelle Localization By Membrane Tethering Membrane Docking Vesicle Docking Protein Transport Establishment Of Protein Localization Vesicle-mediated Transport Secretion By Cell Vesicle Organization Secretion Membrane Organization Establishment Of Localization In Cell Intracellular Protein Localization SNARE Complex Assembly Syntaxin Binding Organelle Localization Intracellular Protein Transport Regulation Of Exocytosis Cellular Localization Intracellular Transport Regulation Of Synaptic Vesicle Priming Regulation Of Vesicle-mediated Transport Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Regulation Of Secretion By Cell Regulated Exocytosis Calcium-ion Regulated Exocytosis Endomembrane System Regulation Of Secretion Zymogen Granule Membrane Phagocytic Vesicle Positive Regulation Of Exocytosis Neutrophil Degranulation Regulation Of Histamine Secretion By Mast Cell Vesicle-mediated Transport In Synapse Neuron Projection Recycling Endosome Membrane Secretory Granule Regulation Of Hormone Secretion Golgi Vesicle Transport Positive Regulation Of Secretion By Cell Regulation Of Regulated Secretory Pathway Synaptic Vesicle Exocytosis Synaptic Vesicle Membrane
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