ITGAE and CHFR

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		ITGAE	CHFR
Description		integrin subunit alpha E	checkpoint with forkhead and ring finger domains
Image
GO Annotations	Cellular Component	Plasma Membrane Integrin Complex External Side Of Plasma Membrane Cell Surface Membrane	Nucleus PML Body
	Molecular Function	Signaling Receptor Activity Metal Ion Binding	Nucleotide Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cell Adhesion Cell-matrix Adhesion Integrin-mediated Signaling Pathway Cell-cell Adhesion	Protein Polyubiquitination Mitotic Cell Cycle Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Protein Destabilization Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Meiotic Spindle Checkpoint Signaling Mitotic G2/M Transition Checkpoint Cell Division
Pathways		Integrin cell surface interactions
Drugs
Diseases
GWAS		Attention deficit hyperactivity disorder ( 18839057)	Cognitive function ( 24684796) Height ( 31562340) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Refractive error ( 32231278) Smoking initiation (ever regular vs never regular) ( 30679032) Smoking status (ever vs never smokers) ( 30643258) Systolic blood pressure x quantitative lifestyle risk score interaction (1df test) ( 32227373) Systolic blood pressure x quantitative lifestyle risk score interaction (2df test) ( 32227373)
Interacting Genes		6 interacting genes: CDH1 CHFR EED ITGB7 MYH10 TRIM54	30 interacting genes: AURKA BRD4 CBLC EEF1G GABBR1 GRB10 GRB14 HDAC1 HDAC2 ITGAE PML RNF125 RNF7 SIRT1 SMARCA4 SMARCB1 SMARCD1 TRIM9 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2I UBE2L1 UBE2N UBE2W WDR47
Entrez ID		3682	55743
HPRD ID		05249	05552
Ensembl ID		ENSG00000083457	ENSG00000072609
Uniprot IDs		P38570	Q96EP1
PDB IDs		8ZJF	1LGP 1LGQ 2XOC 2XOY 2XOZ 2XP0
Enriched GO Terms of Interacting Partners?		Cytoplasmic Side Of Plasma Membrane Cell Adhesion Molecule Binding Symbiont Entry Into Host Cell Cell-matrix Adhesion Involved In Ameboidal Cell Migration Virus Receptor Activity Integrin Alpha4-beta7 Complex Fourth Ventricle Development Regulation Of Adaxial/abaxial Pattern Formation Meiotic Spindle Checkpoint Signaling Myosin II Filament Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle Response To Heparin Cellular Response To Indole-3-methanol Cell Adhesion Cell Migration Response To Indole-3-methanol Response To Gram-positive Bacterium Lamellipodium Regulation Of Protein Catabolic Process At Postsynapse, Modulating Synaptic Transmission Desmosome Assembly Immune Response In Gut-associated Lymphoid Tissue Biological Process Involved In Interaction With Host Third Ventricle Development Pronucleus Sex Chromatin Negative Regulation Of Meiotic Cell Cycle Phase Transition Meiotic Cell Cycle Checkpoint Signaling Flotillin Complex Positive Regulation Of Protein Transport Actomyosin Substrate-dependent Cell Migration, Cell Extension Postsynaptic Actin Cytoskeleton Ventricular Cardiac Muscle Cell Development Supramolecular Fiber GTPase Activating Protein Binding Cerebellar Purkinje Cell Layer Development Chromatin Silencing Complex Cell Motility Gamma-catenin Binding Desmosome Organization Cellular Response To Lithium Ion Positive Regulation Of Establishment Of Protein Localization Protein Localization To Membrane Adult Heart Development Cardiac Myofibril Assembly Lateral Ventricle Development ESC/E(Z) Complex Facultative Heterochromatin Formation	Ubiquitin Conjugating Enzyme Activity Protein Modification By Small Protein Conjugation Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Post-translational Protein Modification Proteolysis Involved In Protein Catabolic Process Ubiquitin-protein Transferase Activity Protein Ubiquitination Protein Modification Process Protein Polyubiquitination Macromolecule Catabolic Process Protein K11-linked Ubiquitination Proteolysis Transferase Activity Protein Monoubiquitination Protein K48-linked Ubiquitination Protein Metabolic Process P53 Binding Negative Regulation Of Cell Communication Negative Regulation Of Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Catabolic Process Positive Regulation Of Stem Cell Population Maintenance Negative Regulation Of Signal Transduction Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Stem Cell Population Maintenance Host-mediated Perturbation Of Viral Transcription Regulation Of Double-strand Break Repair Regulation Of Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Macromolecule Metabolic Process Nucleosomal DNA Binding Positive Regulation Of Double-strand Break Repair Chromatin Remodeling Protein Lysine Deacetylase Activity ATP Binding NpBAF Complex Regulation Of Mitotic Cell Cycle Ubiquitin Protein Ligase Activity RSC-type Complex Regulation Of DNA Repair NBAF Complex Negative Regulation Of Androgen Receptor Signaling Pathway Protein-containing Complex Negative Regulation Of Intracellular Signal Transduction Positive Regulation Of DNA Repair Histone Deacetylase Activity Nucleosome Disassembly
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