ACADSB and ATE1

		ACADSB	ATE1
Description		acyl-CoA dehydrogenase short/branched chain	arginyltransferase 1
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Nucleus Cytoplasm
	Molecular Function	Short-chain 2-methyl Fatty Acyl-CoA Dehydrogenase Activity Acyl-CoA Dehydrogenase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-CH Group Of Donors Short-chain Fatty Acyl-CoA Dehydrogenase Activity Identical Protein Binding Flavin Adenine Dinucleotide Binding	Arginyl-tRNA--protein Transferase Activity Protein Binding Transferase Activity Acyltransferase Activity
	Biological Process	L-isoleucine Catabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Carboxylic Acid Catabolic Process	Ubiquitin-dependent Protein Catabolic Process Response To Oxidative Stress Proteasomal Protein Catabolic Process Protein Arginylation Protein K27-linked Ubiquitination Protein K63-linked Ubiquitination Protein Targeting To Vacuole Involved In Autophagy Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway
Pathways		Branched-chain amino acid catabolism Mitochondrial protein degradation
Drugs		Isoleucine Valproic acid
Diseases		Disorders of fatty-acid oxidation, including: Medium-chain (MC) acyl-CoA dehydrogenase (AD) deficiency (MCADD); Short-chain AD deficiency (SCADD) ; Short-branched-chain AD deficiency (SBCADD) ; Very long-chain AD deficiency (VLCADD) ; Long-chain 3-hydroxyacyl CoA dehydrogenase deficiency (LCHADD) ; Trifunctional protein deficiency (TFP); Carnitine palmitoyltransferase deficiency (CPT); Carnitine-acylcarnitine translocase deficiency (CACT); Systemic primary carnitine deficiency (CDSP)
GWAS		Antidepressant treatment resistance (> 2 drugs prescribed) ( 30700811) Antidepressant treatment resistance (number of drugs prescribed) ( 30700811) Low density lipoprotein cholesterol levels ( 32154731) Lower body strength ( 27325353)	Chronotype ( 30696823)
Interacting Genes		1 interacting genes: ATE1	14 interacting genes: ABRAXAS2 ACADSB ALCAM CTBP2 FAM53B INTS8 NEDD8 NSMCE4A NTAN1 NUP188 PLEKHA1 RBM10 SUV39H1 TIMM17B
Entrez ID		36	11101
HPRD ID		02626	06979
Ensembl ID		ENSG00000196177	ENSG00000107669
Uniprot IDs		A0A0S2Z3P9 P45954	A0A8I5KTH0 A0A8I5KZ24 B3KWA3 B4DK25 B4E107 F5GXE4 F8WAC9 O95260
PDB IDs		2JIF	8TZV 8UAU
Enriched GO Terms of Interacting Partners?		Arginyl-tRNA--protein Transferase Activity Protein Arginylation Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway Protein Targeting To Vacuole Involved In Autophagy Protein K27-linked Ubiquitination Protein Targeting To Vacuole Establishment Of Protein Localization To Vacuole Protein K63-linked Ubiquitination Protein Localization To Vacuole Acyltransferase Activity
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