ATE1 and INTS8

		ATE1	INTS8
Description		arginyltransferase 1	integrator complex subunit 8
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GO Annotations	Cellular Component	Nucleus Cytoplasm	Chromatin Nucleus Nucleoplasm Chromosome Integrator Complex INTAC Complex
	Molecular Function	Arginyl-tRNA--protein Transferase Activity Protein Binding Transferase Activity Acyltransferase Activity	Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Response To Oxidative Stress Proteasomal Protein Catabolic Process Protein Arginylation Protein K27-linked Ubiquitination Protein K63-linked Ubiquitination Protein Targeting To Vacuole Involved In Autophagy Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway	SnRNA Processing Regulation Of Transcription Elongation By RNA Polymerase II SnRNA 3'-end Processing Protein Localization To Chromatin RNA Polymerase II Transcription Initiation Surveillance
Pathways			RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Chronotype ( 30696823)	Keratoconus ( 33649486) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Molybdenum levels ( 26025379) Multiple sclerosis ( 31604244) Type 2 diabetes ( 25102180)
Interacting Genes		14 interacting genes: ABRAXAS2 ACADSB ALCAM CTBP2 FAM53B INTS8 NEDD8 NSMCE4A NTAN1 NUP188 PLEKHA1 RBM10 SUV39H1 TIMM17B	5 interacting genes: ATE1 CTDP1 DSCAM RNF10 TMEM67
Entrez ID		11101	55656
HPRD ID		06979	08626
Ensembl ID		ENSG00000107669	ENSG00000164941
Uniprot IDs		A0A8I5KTH0 A0A8I5KZ24 B3KWA3 B4DK25 B4E107 F5GXE4 F8WAC9 O95260	Q75QN2
PDB IDs		8TZV 8UAU	7CUN 7PKS 7YCX 8RBX 8RBZ 8RC4 8YJB 9EOF 9EP4
Enriched GO Terms of Interacting Partners?			Post-embryonic Retina Morphogenesis In Camera-type Eye Netrin Receptor Binding TFIIF-class Transcription Factor Complex Binding Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Proteasomal Protein Catabolic Process Protein Arginylation Arginyl-tRNA--protein Transferase Activity Netrin-activated Signaling Pathway Regulation Of Axon Extension Involved In Axon Guidance Regulation Of Cell Growth Dendrite Self-avoidance Regulation Of Developmental Growth Positive Regulation Of Axon Extension Involved In Axon Guidance Camera-type Eye Photoreceptor Cell Differentiation Eye Photoreceptor Cell Differentiation Dendritic Spine Development Regulation Of Multicellular Organismal Development Regulation Of Neurogenesis Tat Protein Binding Host-mediated Activation Of Viral Transcription Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Protein Metabolic Process Exit From Mitosis Macromolecule Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Postsynapse To Nucleus Signaling Pathway Negative Regulation Of Schwann Cell Proliferation Negative Regulation Of Glial Cell Proliferation Extrinsic Component Of Postsynaptic Density Membrane Proteolysis Ubiquitin-dependent Protein Catabolic Process Via The N-end Rule Pathway Protein Targeting To Vacuole Involved In Autophagy Protein K27-linked Ubiquitination Negative Regulation Of Centrosome Duplication MKS Complex Filamin Binding Positive Regulation Of Myelination Photoreceptor Cell Differentiation Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Nervous System Development Regulation Of Cell Differentiation Protein Modification Process Negative Regulation Of Cardiac Muscle Tissue Growth
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