NIPAL4 and RNF19B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NIPAL4	RNF19B
Description		NIPA like domain containing 4	ring finger protein 19B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Ubiquitin Ligase Complex Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Membrane Cytolytic Granule
	Molecular Function	Protein Binding Magnesium Ion Transmembrane Transporter Activity	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Ubiquitin Conjugating Enzyme Binding Ubiquitin Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Monoatomic Ion Transport Magnesium Ion Transport Magnesium Ion Transmembrane Transport	Adaptive Immune Response Immune System Process Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Natural Killer Cell Mediated Cytotoxicity Protein Autoubiquitination
Pathways		Miscellaneous transport and binding events	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Lamellar ichthyosis (LI) and Non-bullous congenital ichthyosiform erythroderma (NBCIE)
GWAS		Asthma ( 31959851)	Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269)
Interacting Genes		15 interacting genes: ACKR2 CLDN7 CMTM2 COMT FFAR2 GJB1 GPR152 HHLA2 IL10RA LHFPL5 RNF185 RNF19B SSMEM1 TM4SF18 TRHR	30 interacting genes: APOL3 ASGR1 CDIPT CLEC1A DHODH FDPS GIMAP5 GOSR2 ICMT MEST MS4A1 NIPAL4 PPP1CC RAP1GDS1 SACM1L SEC22A SEC23A SELENOK SLC30A3 SLC61A1 TAP1 TMEM100 TMEM120B TMEM208 TMEM31 TNF TSPAN2 UBE2D2 UBE2D3 UBE2L3
Entrez ID		348938	127544
HPRD ID		19424	13725
Ensembl ID		ENSG00000172548	ENSG00000116514
Uniprot IDs		Q0D2K0	Q6ZMZ0
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane	Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Ubiquitin Conjugating Enzyme Activity
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