ZFP57 and CIB3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZFP57	CIB3
Description		ZFP57 zinc finger protein	calcium and integrin binding family member 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Magnesium Ion Binding Calcium Ion Binding Protein Binding Metal Ion Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Autosome Genomic Imprinting	Calcium Ion Homeostasis
Pathways
Drugs
Diseases		Transient neonatal diabetes mellitus (TNDM)
GWAS		Albumin-globulin ratio ( 29403010) Autism spectrum disorder or schizophrenia ( 28540026) Hip circumference adjusted for BMI ( 34021172) Offspring birth weight ( 31043758) Sepsis (hospital admission) ( 32592749) White matter integrity (mean diffusivity) ( 32358547)	Lymphocyte count ( 32888494)
Interacting Genes		9 interacting genes: CFTR CIB3 DVL3 EMD KANK2 MKRN3 MLH1 POLR1C YOD1	53 interacting genes: ARMC8 BEND7 C17orf50 ENOX2 GMCL1 KASH5 KLF17 LNX1 MEOX1 MEOX2 NANOS3 NME4 PAX5 PAX6 POLR2G POU6F2 RBAK REL SCNM1 SERTAD1 SLPI SP3 SP4 SYPL1 TACC3 TLE5 TRAF5 TRIM14 TRIM2 ZBTB43 ZC2HC1C ZFP1 ZFP57 ZNF146 ZNF177 ZNF180 ZNF19 ZNF276 ZNF317 ZNF329 ZNF398 ZNF426 ZNF552 ZNF559-ZNF177 ZNF578 ZNF597 ZNF620 ZNF664 ZNF688 ZNF774 ZNF835 ZSCAN4 ZSCAN5A
Entrez ID		346171	117286
HPRD ID		19560	16713
Ensembl ID		ENSG00000204644	ENSG00000141977
Uniprot IDs		A0A1U9X8V5 A0A7I2S1M6 B7ZW61 Q9NU63	Q96Q77
PDB IDs			6WU5 6WU7 6WUD
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Regulation Of Protein Localization Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding TMEM240-body Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Chiasma Late Recombination Nodule Meiotic Metaphase I Homologous Chromosome Alignment Negative Regulation Of Vitamin D Receptor Signaling Pathway Regulation Of Establishment Of Protein Localization Regulation Of Cellular Localization Positive Regulation Of Enamel Mineralization Regulation Of Protein Transport Positive Regulation Of Monoatomic Anion Transport Guanine/thymine Mispair Binding Male Meiosis Chromosome Segregation MutLalpha Complex Negative Regulation Of Mitotic Recombination Protein K29-linked Deubiquitination Protein K27-linked Deubiquitination Transepithelial Water Transport Regulation Of Intracellular Protein Transport Homologous Chromosome Segregation Female Meiosis Chromosome Segregation Mismatch Repair Complex Protein K33-linked Deubiquitination	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Zinc Ion Binding DNA Binding Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Metal Ion Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Sequence-specific Double-stranded DNA Binding Nucleus Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Protein Binding DNA-binding Transcription Factor Activity RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Somite Specification DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific DNA Binding HMG Box Domain Binding Embryonic Camera-type Eye Morphogenesis Segment Specification Somite Development Chromatin
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