HMOX2 and PLXNB2

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		HMOX2	PLXNB2
Description		heme oxygenase 2	plexin B2
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Specific Granule Membrane	Semaphorin Receptor Complex Plasma Membrane Cell Surface Membrane Extracellular Exosome
	Molecular Function	Heme Oxygenase (decyclizing) Activity Protein Binding Oxidoreductase Activity Heme Binding Metal Ion Binding	Transmembrane Signaling Receptor Activity Protein Binding Semaphorin Receptor Activity Signaling Receptor Activity
	Biological Process	Response To Hypoxia Heme Oxidation Response To Oxidative Stress Heme Catabolic Process	Neural Tube Closure Regulation Of Protein Phosphorylation Cytoplasmic Translation Receptor-mediated Endocytosis Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Negative Regulation Of Cell Adhesion Neuroblast Proliferation Synapse Assembly Brain Development Regulation Of Cell Shape Regulation Of Neuron Projection Development Positive Regulation Of Neuron Projection Development Regulation Of Cell Migration Positive Regulation Of Cell Projection Organization Negative Regulation Of Translation In Response To Stress Cellular Response To Stress TRNA Stabilization Regulation Of GTPase Activity Positive Regulation Of Translation Positive Regulation Of Axonogenesis Regulation Of Protein Metabolic Process Semaphorin-plexin Signaling Pathway Excitatory Synapse Assembly Regulation Of Neuron Migration
Pathways		Heme degradation Neutrophil degranulation RHOA GTPase cycle Iron uptake and transport Cytoprotection by HMOX1
Drugs		NADH Stannsoporfin
Diseases
GWAS		Erectile dysfunction ( 30583798)	Acne (severe) ( 24927181) Blond vs. brown/black hair color ( 30531825) Blood protein levels ( 30072576) Cutaneous malignant melanoma ( 32341527) Cutaneous melanoma or hair colour ( 32341527) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Lymphocyte count ( 32888494) Nevus count or cutaneous melanoma ( 32341527) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Sensorimotor dexterity ( 31596458) Systolic blood pressure ( 30224653)
Interacting Genes		68 interacting genes: A2M APP AQP6 ARL13B ASGR2 ATP5F1B BCL2L13 BIK BLOC1S2 CCR2 CD79A CEBPZ CEP126 COPS6 CRB3 CSNK2A1 EBP EEF1G EIF3C ELOVL4 ERGIC3 F2RL1 FAM209A FAM210B GET1 GIT1 GPR152 GPRASP1 GPX8 HAP1 IMMT INPP5K ITFG1 JADE1 KCNJ6 KCNMA1 LAPTM5 LRIF1 MARK3 MED31 MGST3 MTNR1A NDUFS2 NKRF NR3C1 PCNT PLXNB2 PTGER4 RBBP4 RETREG3 RNASEK SAR1A SETDB1 SGPL1 SHC1 SKA2 SLC30A8 SMO SNX5 SNX7 SSMEM1 STOM SYT1 TMEM14B TMX2 VMA21 ZFP28 ZNF746	9 interacting genes: AIFM2 ARHGEF11 ARHGEF12 CENPU HDLBP HMOX2 PFDN1 PTN RND1
Entrez ID		3163	23654
HPRD ID		00783	05050
Ensembl ID		ENSG00000103415	ENSG00000196576
Uniprot IDs		A0A087WT44 B3KSE0 P30519	O15031
PDB IDs		2Q32 2QPP 2RGZ 4WMH 5UC8 5UC9 5UCA	4E71
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?