ZBTB48 and PDPN

		ZBTB48	PDPN
Description		zinc finger and BTB domain containing 48	podoplanin
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GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleus Chromosome	Ruffle Cytoplasm Mitochondrion Cytosol Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lamellipodium Cell Junction Filopodium Lamellipodium Membrane Cytoplasmic Vesicle Filopodium Membrane Microvillus Membrane Ruffle Membrane Cell Projection Membrane Raft Leading Edge Of Lamellipodium Anchoring Junction Tetraspanin-enriched Microdomain
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Double-stranded Telomeric DNA Binding DNA-binding Transcription Factor Activity RNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding	Signaling Receptor Binding Water Transmembrane Transporter Activity Protein Binding Folic Acid Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Water Channel Activity Chemokine Binding Protein-folding Chaperone Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Telomere Maintenance Via Telomere Lengthening Positive Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process	Lymphangiogenesis Water Transport Amino Acid Transport Cell Adhesion Signal Transduction Rho Protein Signal Transduction Negative Regulation Of Cell Population Proliferation Regulation Of Cell Shape Positive Regulation Of Epithelial To Mesenchymal Transition Folic Acid Transport Cell Migration Platelet Activation Lung Development Positive Regulation Of Cell Migration Negative Regulation Of Apoptotic Process Wound Healing, Spreading Of Cells Lymph Node Development Lymphatic Endothelial Cell Fate Commitment Actin-mediated Cell Contraction Positive Regulation Of Extracellular Matrix Disassembly Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Platelet Aggregation Regulation Of Myofibroblast Contraction Regulation Of Lamellipodium Morphogenesis
Pathways			GPVI-mediated activation cascade Specification of primordial germ cells
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654)
Interacting Genes		36 interacting genes: C11orf58 CDK2AP2 CDKN1A CEP70 DVL2 DVL3 EP300 GPATCH2L ILK KRTAP1-1 KRTAP10-5 KRTAP10-7 L3MBTL2 LLCFC1 MAP1LC3A MCC NME7 PDPN PNRC2 RGS2 RNF10 SPANXN2 THAP1 TNFRSF14 TRIM41 TSPYL2 UPF2 WDR5 ZBTB26 ZBTB6 ZBTB7A ZBTB8A ZBTB9 ZNF317 ZNF408 ZNF837	7 interacting genes: CELA2B LHX1 PRDM2 PRMT1 TMEM14B TOM1L1 ZBTB48
Entrez ID		3104	10630
HPRD ID		01316	16398
Ensembl ID		ENSG00000204859	ENSG00000162493
Uniprot IDs		A8K291 B2R702 P10074	Q86YL7
PDB IDs		3B84 5YJ3	3WSR 4YO0 5XCV 7C94 7CQC 7CQD
Enriched GO Terms of Interacting Partners?		Zinc Ion Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Nucleus Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of DNA-templated Transcription Positive Regulation Of Neuron Projection Arborization Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Neuron Projection Arborization	Sequence-specific DNA Binding Histone Methyltransferase Activity GATOR1 Complex Binding Cervix Development Cerebellar Purkinje Cell-granule Cell Precursor Cell Signaling Metanephric Comma-shaped Body Morphogenesis Uterine Epithelium Development Positive Regulation Of Anterior Head Development Dorsal Spinal Cord Interneuron Posterior Axon Guidance Nephric Duct Elongation Ectoderm Formation Metanephric Glomerulus Development Metanephric Renal Vesicle Morphogenesis Renal Vesicle Morphogenesis Spinal Cord Interneuron Axon Guidance DNA-binding Transcription Factor Activity Regulation Of Hemoglobin Biosynthetic Process Protein-arginine Omega-N Monomethyltransferase Activity N-methyltransferase Activity Mitogen-activated Protein Kinase P38 Binding Response To Methionine Histone H4R3 Methyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone H4 Methyltransferase Activity Methyltransferase Activity Cellular Response To Methionine Methylation Positive Regulation Of Hemoglobin Biosynthetic Process Peptidyl-arginine Methylation Metanephric Part Of Ureteric Bud Development Pronephros Development Interneuron Axon Guidance Mesendoderm Development Oviduct Development Positive Regulation Of Gastrulation Lateral Motor Column Neuron Migration Oviduct Epithelium Development Anterior/posterior Axon Guidance Embryonic Retina Morphogenesis In Camera-type Eye Ureter Morphogenesis Spinal Cord Motor Neuron Migration S-shaped Body Morphogenesis Nephric Duct Development Positive Regulation Of Nephron Tubule Epithelial Cell Differentiation Comma-shaped Body Morphogenesis Mesonephric Duct Development Forebrain Regionalization Paramesonephric Duct Development Metanephric S-shaped Body Morphogenesis Histone H3K9 Trimethyltransferase Activity
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