PDPN and CELA2B

		PDPN	CELA2B
Description		podoplanin	chymotrypsin like elastase 2B
Image			No pdb structure
GO Annotations	Cellular Component	Ruffle Cytoplasm Mitochondrion Cytosol Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Lamellipodium Cell Junction Filopodium Lamellipodium Membrane Cytoplasmic Vesicle Filopodium Membrane Microvillus Membrane Ruffle Membrane Cell Projection Membrane Raft Leading Edge Of Lamellipodium Anchoring Junction Tetraspanin-enriched Microdomain	Extracellular Region Extracellular Space
	Molecular Function	Signaling Receptor Binding Water Transmembrane Transporter Activity Protein Binding Folic Acid Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Water Channel Activity Chemokine Binding Protein-folding Chaperone Binding	Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity
	Biological Process	Lymphangiogenesis Water Transport Amino Acid Transport Cell Adhesion Signal Transduction Rho Protein Signal Transduction Negative Regulation Of Cell Population Proliferation Regulation Of Cell Shape Positive Regulation Of Epithelial To Mesenchymal Transition Folic Acid Transport Cell Migration Platelet Activation Lung Development Positive Regulation Of Cell Migration Negative Regulation Of Apoptotic Process Wound Healing, Spreading Of Cells Lymph Node Development Lymphatic Endothelial Cell Fate Commitment Actin-mediated Cell Contraction Positive Regulation Of Extracellular Matrix Disassembly Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Platelet Aggregation Regulation Of Myofibroblast Contraction Regulation Of Lamellipodium Morphogenesis	Proteolysis
Pathways		GPVI-mediated activation cascade Specification of primordial germ cells
Drugs
Diseases
GWAS			Alcoholic chronic pancreatitis ( 28754779) Body mass index ( 29273807) Body size at age 10 ( 32376654) Estimated glomerular filtration rate ( 31015462) Hemoglobin ( 32888494) Resistant hypertension ( 30237584)
Interacting Genes		7 interacting genes: CELA2B LHX1 PRDM2 PRMT1 TMEM14B TOM1L1 ZBTB48	6 interacting genes: CALCOCO2 KAZN KRT40 KRTAP3-1 PDPN ZDHHC15
Entrez ID		10630	51032
HPRD ID		16398	06496
Ensembl ID		ENSG00000162493	ENSG00000215704
Uniprot IDs		Q86YL7	P08218 Q6ISP9
PDB IDs		3WSR 4YO0 5XCV 7C94 7CQC 7CQD
Enriched GO Terms of Interacting Partners?		Sequence-specific DNA Binding Histone Methyltransferase Activity GATOR1 Complex Binding Cervix Development Cerebellar Purkinje Cell-granule Cell Precursor Cell Signaling Metanephric Comma-shaped Body Morphogenesis Uterine Epithelium Development Positive Regulation Of Anterior Head Development Dorsal Spinal Cord Interneuron Posterior Axon Guidance Nephric Duct Elongation Ectoderm Formation Metanephric Glomerulus Development Metanephric Renal Vesicle Morphogenesis Renal Vesicle Morphogenesis Spinal Cord Interneuron Axon Guidance DNA-binding Transcription Factor Activity Regulation Of Hemoglobin Biosynthetic Process Protein-arginine Omega-N Monomethyltransferase Activity N-methyltransferase Activity Mitogen-activated Protein Kinase P38 Binding Response To Methionine Histone H4R3 Methyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone H4 Methyltransferase Activity Methyltransferase Activity Cellular Response To Methionine Methylation Positive Regulation Of Hemoglobin Biosynthetic Process Peptidyl-arginine Methylation Metanephric Part Of Ureteric Bud Development Pronephros Development Interneuron Axon Guidance Mesendoderm Development Oviduct Development Positive Regulation Of Gastrulation Lateral Motor Column Neuron Migration Oviduct Epithelium Development Anterior/posterior Axon Guidance Embryonic Retina Morphogenesis In Camera-type Eye Ureter Morphogenesis Spinal Cord Motor Neuron Migration S-shaped Body Morphogenesis Nephric Duct Development Positive Regulation Of Nephron Tubule Epithelial Cell Differentiation Comma-shaped Body Morphogenesis Mesonephric Duct Development Forebrain Regionalization Paramesonephric Duct Development Metanephric S-shaped Body Morphogenesis Histone H3K9 Trimethyltransferase Activity	Regulation Of Myofibroblast Contraction Folic Acid Transmembrane Transporter Activity Leading Edge Of Lamellipodium Lymphatic Endothelial Cell Fate Commitment Water Transmembrane Transporter Activity Keratin Filament Structural Molecule Activity Intermediate Filament Protein-cysteine S-myristoyltransferase Activity Protein Targeting To Golgi Apparatus Xenophagy Positive Regulation Of Autophagosome Maturation Chemokine Binding Protein-cysteine S-stearoyltransferase Activity Folic Acid Transport Synaptic Vesicle Maturation Positive Regulation Of Extracellular Matrix Disassembly Positive Regulation Of Platelet Aggregation Regulation Of Lamellipodium Morphogenesis Tetraspanin-enriched Microdomain Epithelial Cell Fate Commitment Peptidyl-L-cysteine S-palmitoylation Positive Regulation Of Cellular Component Organization Regulation Of Autophagosome Maturation Lymphangiogenesis Water Channel Activity Positive Regulation Of Dendrite Development Positive Regulation Of Homotypic Cell-cell Adhesion Lymph Node Development Filopodium Membrane Protein Palmitoylation Palmitoyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity
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