ERO1A and GRSF1

Number of citations of the paper that reports this interaction (PubMedID 32645484)
0

Data Source:
BioGRID (two hybrid)

		ERO1A	GRSF1
Description		endoplasmic reticulum oxidoreductase 1 alpha	G-rich RNA sequence binding factor 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Lumen Membrane Dendrite Cell Projection Intracellular Membrane-bounded Organelle	Nucleoplasm Cytoplasm Mitochondrion Mitochondrial Matrix Ribonucleoprotein Granule Mitochondrial Nucleoid Ribonucleoprotein Complex
	Molecular Function	Protein Binding Protein-disulfide Reductase Activity Oxidoreductase Activity Thiol Oxidase Activity FAD Binding	G-quadruplex RNA Binding Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Protein Folding Apoptotic Process Response To Oxidative Stress Transforming Growth Factor Beta Receptor Signaling Pathway Skeletal Muscle Tissue Development Response To Temperature Stimulus L-ascorbic Acid Metabolic Process Extracellular Matrix Organization Collagen Fibril Organization Endoplasmic Reticulum Unfolded Protein Response Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Protein Modification Process Cell Redox Homeostasis Brown Fat Cell Differentiation Release Of Sequestered Calcium Ion Into Cytosol Protein Maturation Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress Cellular Response To Hypoxia	Mitochondrial RNA Catabolic Process Positive Regulation Of Mitochondrial RNA Catabolic Process MRNA Processing TRNA Processing Anterior/posterior Pattern Specification Morphogenesis Of Embryonic Epithelium Regulation Of RNA Splicing
Pathways		Detoxification of Reactive Oxygen Species	Viral mRNA Translation Mitochondrial RNA degradation
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549) Urine 6-bromotryptophan levels in chronic kidney disease ( 32572055)	Type 2 diabetes ( 30718926)
Interacting Genes		16 interacting genes: APPBP2 DYNLT1 EBF1 ERP44 GPX7 GPX8 GRSF1 KLHDC2 LHX4 LINC01554 OGT P4HB PDIA3 PDILT PELI2 RHOU	55 interacting genes: AUP1 BTBD6 CNRIP1 COMMD1 CYC1 DACT1 EIF1B ERO1A FADS2 FNTA FYN GSE1 GTF2E2 HCFC2 HIVEP3 ISYNA1 MAP6 MIR1-2 MIR106B MIR18B MIR200B MIR200C MIR205 MIR25 MIR31 MIR451A MIR9-1 MIR9-2 MIR92A1 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F2 MIRLET7G MIRLET7I NEUROD2 NOP53 NUP153 NUP93 OGT PIN1 PPIA PRNP PSMD10 RAB3A RING1 SLC25A21-AS1 UBE3C VPS11 ZNF3
Entrez ID		30001	2926
HPRD ID		13278	07276
Ensembl ID		ENSG00000197930	ENSG00000132463
Uniprot IDs		Q96HE7	Q12849
PDB IDs		3AHQ 3AHR	2LMI 4QU6 4QU7
Enriched GO Terms of Interacting Partners?		Protein Disulfide Isomerase Activity Endoplasmic Reticulum Lumen Protein Folding Protein Folding In Endoplasmic Reticulum Cellular Response To Interleukin-7 Response To Interleukin-7 Cul2-RING Ubiquitin Ligase Complex Glutathione Peroxidase Activity Protein-disulfide Reductase Activity Peroxidase Activity Isomerase Activity Transport Of Viral Material Towards Nucleus Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Response To Endoplasmic Reticulum Stress	MiRNA-mediated Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process Extracellular Vesicle MRNA 3'-UTR Binding Negative Regulation Of Translation MRNA Destabilization Negative Regulation Of Protein Metabolic Process RNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cell Motility Negative Regulation Of Signal Transduction Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Locomotion Negative Regulation Of Interleukin-6-mediated Signaling Pathway Negative Regulation Of Signaling Negative Regulation Of Cell Communication Regulation Of Protein Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Translation Negative Regulation Of Cell Migration Regulation Of MRNA Stability Positive Regulation Of Catabolic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of RNA Stability Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Metabolic Process Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Intracellular Signal Transduction Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Endothelial Cell Migration Regulation Of Signal Transduction Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Angiogenesis Regulation Of MRNA Metabolic Process Regulation Of Vasculature Development
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