SNX8 and RABAC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SNX8	RABAC1
Description		sorting nexin 8	Rab acceptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Cytosol Membrane Retromer Complex Cytoplasmic Vesicle Early Endosome Membrane	Cytoplasm Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse Presynapse Glutamatergic Synapse
	Molecular Function	Protein Binding Lipid Binding Phosphatidylinositol Binding Identical Protein Binding	Protein Binding Identical Protein Binding GTPase Binding Proline-rich Region Binding
	Biological Process	Intracellular Protein Transport Protein Transport Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Dimensional psychopathology (Social) ( 29496196) LDL cholesterol ( 30275531) Mean platelet volume ( 32888494) Neuropathic pain in head and neck cancer ( 29884837) Red blood cell count ( 32888494) Schizophrenia ( 22688191 23974872) Thyroid stimulating hormone levels ( 32769997)	Brain morphology (MOSTest) ( 32665545) Left-handedness ( 32989287)
Interacting Genes		6 interacting genes: ARL6IP1 C14orf119 FASN RABAC1 REEP6 WEE2-AS1	98 interacting genes: ABHD4 AQP6 C6orf47 CMTM3 COQ8A CRB3 CREB3 CYB5R3 CYBRD1 DUSP12 EI24 EMP1 F11R FHIP1B FXR1 FXR2 GDI1 GPR152 HRAS HRG HSD17B13 LEMD3 LMNA LNX1 LTBR MAD2L1 MCF2L MIEF2 NAT14 NDRG2 NDRG4 NIF3L1 NR3C2 NTAQ1 NUDT18 PBX3 PLEKHF2 PLK1 RAB17 RAB1A RAB22A RAB33A RAB3A RAB4A RAB4B RAB5A RAB5B RAB5C RAB6A RAB7A RAP1A RASD2 REEP2 REEP5 RETREG3 RGS2 RHEB RHOA RIC8A RIMS2 RIN3 RNF5 RPS20 RRAS2 S100B SGK1 SH3GL3 SH3GLB1 SLAMF6 SLC10A1 SLC18A1 SNCA SNX1 SNX10 SNX11 SNX15 SNX17 SNX8 SPG21 SSR3 STIM1 STOML2 SYT16 TMEM115 TMEM14B TMEM42 TMX2 TNIP1 TRIM32 TSHR TUBB2A TXN2 UBE2I VAMP2 VIM VTA1 WIPI2 ZFYVE21
Entrez ID		29886	10567
HPRD ID		11592	05375
Ensembl ID		ENSG00000106266	ENSG00000105404
Uniprot IDs		Q9Y5X2	Q9UI14
PDB IDs
Enriched GO Terms of Interacting Partners?		Fatty Acid Synthase Activity [acyl-carrier-protein] S-acetyltransferase Activity [acyl-carrier-protein] S-malonyltransferase Activity (3R)-hydroxyacyl-[acyl-carrier-protein] Dehydratase Activity Fatty Acyl-[ACP] Hydrolase Activity Phosphopantetheine Binding Endoplasmic Reticulum Organization 3-oxoacyl-[acyl-carrier-protein] Synthase Activity Enoyl-[acyl-carrier-protein] Reductase (NADPH) Activity 3-oxoacyl-[acyl-carrier-protein] Reductase (NADPH) Activity Positive Regulation Of L-glutamate Import Across Plasma Membrane Pre-mRNA 5'-splice Site Binding Glycogen Granule Sec61 Translocon Complex Regulation Of Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Formation Neutrophil Differentiation Endoplasmic Reticulum Tubular Network Membrane Organization MRNA 5'-splice Site Recognition Regulation Of L-glutamate Import Across Plasma Membrane Response To Caloric Restriction Ether Lipid Biosynthetic Process Establishment Of Endothelial Intestinal Barrier Endoplasmic Reticulum Membrane Organization Cotranslational Protein Targeting To Membrane Ether Lipid Metabolic Process Monocyte Differentiation Proline-rich Region Binding Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Detection Of Light Stimulus Involved In Visual Perception U1 SnRNP Positive Regulation Of Amino Acid Transport Cellular Response To Interleukin-4 Fatty-acyl-CoA Biosynthetic Process Response To Interleukin-4 Granulocyte Differentiation Acetyl-CoA Metabolic Process	GTPase Activity GTP Binding GDP Binding Membrane Endosome G Protein Activity Establishment Of Localization In Cell Vesicle-mediated Transport Protein Transport Intracellular Protein Localization Establishment Of Protein Localization Cellular Localization Intracellular Protein Transport Protein Binding Endosomal Transport Regulation Of Neuronal Synaptic Plasticity Lipid Binding Secretory Granule Membrane Intracellular Transport Phosphatidylinositol Binding Endocytosis Vesicle Organization Regulation Of Long-term Neuronal Synaptic Plasticity Early Endosome Regulation Of Cellular Component Organization Endosome Organization Regulation Of Vesicle-mediated Transport Vesicle-mediated Transport In Synapse Synaptic Vesicle Exocytosis Localization Within Membrane Clathrin-sculpted Monoamine Transport Vesicle Membrane Rab Protein Signal Transduction Import Into Cell Early Endosome To Golgi Transport Early Endosome Membrane Endomembrane System Cytoplasmic Vesicle Endoplasmic Reticulum Membrane Organelle Organization Synaptic Vesicle Membrane Identical Protein Binding Autophagosome Assembly Plasma Membrane To Endosome Transport Small GTPase-mediated Signal Transduction Regulation Of Synaptic Plasticity Establishment Of Organelle Localization Autophagosome Organization Endosome Membrane Endocytic Vesicle Organelle Localization
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