SNX8

Description		sorting nexin 8
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Cytosol Membrane Retromer Complex Cytoplasmic Vesicle Early Endosome Membrane
	Molecular Function	Protein Binding Lipid Binding Phosphatidylinositol Binding Identical Protein Binding
	Biological Process	Intracellular Protein Transport Protein Transport Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Dimensional psychopathology (Social) ( 29496196) LDL cholesterol ( 30275531) Mean platelet volume ( 32888494) Neuropathic pain in head and neck cancer ( 29884837) Red blood cell count ( 32888494) Schizophrenia ( 22688191 23974872) Thyroid stimulating hormone levels ( 32769997)
Novel Interacting Genes		6 novel interacting genes: ARL6IP1 C14orf119 FASN RABAC1 REEP6 WEE2-AS1
Interacting Genes		6 interacting genes: ARL6IP1 C14orf119 FASN RABAC1 REEP6 WEE2-AS1
Entrez ID		29886
HPRD ID		11592
Ensembl ID		ENSG00000106266
Uniprot IDs		Q9Y5X2
PDB IDs
Enriched GO Terms of Interacting Partners?		Fatty Acid Synthase Activity [acyl-carrier-protein] S-acetyltransferase Activity [acyl-carrier-protein] S-malonyltransferase Activity (3R)-hydroxyacyl-[acyl-carrier-protein] Dehydratase Activity Fatty Acyl-[ACP] Hydrolase Activity Phosphopantetheine Binding Endoplasmic Reticulum Organization 3-oxoacyl-[acyl-carrier-protein] Synthase Activity Enoyl-[acyl-carrier-protein] Reductase (NADPH) Activity 3-oxoacyl-[acyl-carrier-protein] Reductase (NADPH) Activity Positive Regulation Of L-glutamate Import Across Plasma Membrane Pre-mRNA 5'-splice Site Binding Glycogen Granule Sec61 Translocon Complex Regulation Of Endoplasmic Reticulum Tubular Network Organization Endoplasmic Reticulum Tubular Network Formation Neutrophil Differentiation Endoplasmic Reticulum Tubular Network Membrane Organization MRNA 5'-splice Site Recognition Regulation Of L-glutamate Import Across Plasma Membrane Response To Caloric Restriction Ether Lipid Biosynthetic Process Establishment Of Endothelial Intestinal Barrier Endoplasmic Reticulum Membrane Organization Cotranslational Protein Targeting To Membrane Ether Lipid Metabolic Process Monocyte Differentiation Proline-rich Region Binding Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Detection Of Light Stimulus Involved In Visual Perception U1 SnRNP Positive Regulation Of Amino Acid Transport Cellular Response To Interleukin-4 Fatty-acyl-CoA Biosynthetic Process Response To Interleukin-4 Granulocyte Differentiation Acetyl-CoA Metabolic Process
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