TPRG1 and TMEM120A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TPRG1	TMEM120A
Description		tumor protein p63 regulated 1	transmembrane protein 120A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Nucleus Nuclear Inner Membrane Endoplasmic Reticulum Plasma Membrane Membrane
	Molecular Function	Protein Binding	Monoatomic Ion Channel Activity Protein Binding Coenzyme A Binding
	Biological Process		Immune System Process Monoatomic Ion Transmembrane Transport Innate Immune Response Fat Cell Differentiation Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain Protein Homooligomerization Protein Heterooligomerization Antiviral Innate Immune Response
Pathways
Drugs
Diseases
GWAS		Allergic rhinitis ( 30013184) Asthma ( 31959851) Axial length ( 24144296) Cutaneous squamous cell carcinoma ( 32041948) Femur bone mineral density x serum urate levels interaction ( 34046847) Hair color ( 26926045) Squamous cell carcinoma ( 26829030)	Coffee consumption ( 25288136) Coffee consumption (cups per day) ( 25288136) Sarcoidosis ( 32826979)
Interacting Genes		19 interacting genes: APOC1 APOC2 APOC4 AQP6 CGRRF1 CIDEB EBAG9 FCER1G HSD17B11 HSD17B13 REEP4 RETREG3 RHBDD2 SCN3B SLC10A6 SLC35H1 SLC71A2 TMEM120A TMX2	24 interacting genes: AQP6 CYBRD1 FAM209A FBXO7 GOT1 GPRC5B HSD17B13 LEPROT LRRC25 ORMDL2 PAXIP1 PPP1CC PTAFR SCN3B STX1A STX2 TMEM14B TMEM35A TMEM86B TMX2 TPRG1 TSPAN18 UBC VKORC1
Entrez ID		285386	83862
HPRD ID		13451	15543
Ensembl ID		ENSG00000188001	ENSG00000189077
Uniprot IDs		Q6ZUI0	A0A087X266 Q9BXJ8
PDB IDs			7CXR 7F3T 7F3U 7F6V 7N7P
Enriched GO Terms of Interacting Partners?		High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Steroid Dehydrogenase Activity Acylglycerol Homeostasis Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Triglyceride Homeostasis Regulation Of Triglyceride Metabolic Process Endoplasmic Reticulum Lipid Transport Regulation Of Phospholipid Catabolic Process Lipase Inhibitor Activity Organic Hydroxy Compound Transport Very-low-density Lipoprotein Particle Assembly Chylomicron Phospholipid Efflux Lipid Droplet Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Negative Regulation Of Lipoprotein Particle Clearance Negative Regulation Of Cholesterol Transport Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Plasma Lipoprotein Particle Assembly Protein-lipid Complex Assembly Regulation Of Lipid Metabolic Process Plasma Lipoprotein Particle Clearance Organophosphate Ester Transport Cholesterol Efflux Negative Regulation Of Receptor-mediated Endocytosis Lipoprotein Metabolic Process Lipid Storage Regulation Of Phospholipid Metabolic Process Plasma Lipoprotein Particle Remodeling Lipid Homeostasis Protein-containing Complex Remodeling Negative Regulation Of Lipid Transport Negative Regulation Of Phosphatidylcholine Catabolic Process Nitrate Transmembrane Transporter Activity Transmembrane Transport IgE Receptor Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport Regulation Of Lipid Biosynthetic Process Regulation Of Fatty Acid Biosynthetic Process Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Regulation Of Lipid Catabolic Process Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling PH-gated Chloride Channel Activity Nitrate Transmembrane Transport
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