TMED8 and ZDHHC16

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMED8	ZDHHC16
Description		transmembrane p24 trafficking protein family member 8	zDHHC palmitoyltransferase 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane
	Molecular Function	Protein Binding	Protein Binding Palmitoyltransferase Activity Transferase Activity Acyltransferase Activity Protein-cysteine S-palmitoyltransferase Activity
	Biological Process		Eye Development Apoptotic Process DNA Damage Response Heart Development Telencephalon Development Fibroblast Growth Factor Receptor Signaling Pathway Involved In Forebrain Neuron Fate Commitment
Pathways
Drugs
Diseases
GWAS			Early spontaneous preterm birth ( 31194736) Spontaneous preterm birth with premature rupture of membranes ( 31194736)
Interacting Genes		33 interacting genes: ADTRP AMIGO2 APOL2 ARL6IP1 C10orf67 CIAO2A CMTM5 CMTM6 CYB561D1 DEFB129 DERL1 DGAT2L6 EI24 H4C7 LAPTM4A MDK MMGT1 MRPL41 MRPS18B MTIF3 NDUFA12 PROX2 REEP6 SERP2 STX8 SUSD3 TMEM115 TMEM121 TMEM218 TMEM254 TRAM1L1 UNC50 ZDHHC16	5 interacting genes: ABL1 FOXP1 MTNR1A TMED8 YIF1A
Entrez ID		283578	84287
HPRD ID		18201	15712
Ensembl ID		ENSG00000100580	ENSG00000171307
Uniprot IDs		Q6PL24	B1AMU0 B4DNL2 Q969W1
PDB IDs
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane	Transitional One Stage B Cell Differentiation Alpha-beta T Cell Activation T Cell Differentiation Lymphocyte Activation Involved In Immune Response Microspike Assembly Regulation Of Endothelial Cell Migration Alpha-beta T Cell Differentiation Nicotinate-nucleotide Adenylyltransferase Activity Cell Activation Involved In Immune Response B-1 B Cell Homeostasis Podocyte Apoptotic Process DN4 Thymocyte Differentiation Leukocyte Activation Involved In Immune Response Positive Regulation Of Phospholipase C/protein Kinase C Signal Transduction Cerebellum Morphogenesis Protein Localization To Microtubule Plus-end Protein Localization To Cytoplasmic Microtubule Plus-end Regulation Of Morphogenesis Of An Epithelium Phospholipase C-inhibiting G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Establishment Of T Cell Polarity Positive Regulation Of Endothelial Cell Migration Vascular Endothelial Cell Response To Oscillatory Fluid Shear Stress B Cell Proliferation Involved In Immune Response Neuropilin Signaling Pathway Melatonin Receptor Activity Positive Regulation Of Interleukin-21 Production Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Regulation Of Establishment Of T Cell Polarity Supercoiled DNA Binding Positive Regulation Of Blood Vessel Branching Regulation Of Macrophage Colony-stimulating Factor Production Mitochondrial Depolarization Lymphocyte Differentiation Cellular Response To Dopamine Osteoclast Development Regulation Of Endothelial Tube Morphogenesis Platelet-derived Growth Factor Receptor-beta Signaling Pathway Regulation Of Blood Vessel Branching Response To Dopamine Bubble DNA Binding Positive Regulation Of B Cell Receptor Signaling Pathway Delta-catenin Binding Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Activated T Cell Proliferation Bergmann Glial Cell Differentiation Monocyte Activation Endothelial Cell Activation T Cell Activation Negative Regulation Of Ubiquitin-protein Transferase Activity Response To Lipopolysaccharide
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