IL17B and IL17RB

Number of citations of the paper that reports this interaction (PubMedID 10749887)
0

Data Source:
HPRD (in vitro, in vivo)

		IL17B	IL17RB
Description		interleukin 17B	interleukin 17 receptor B
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Cytoplasm Plasma Membrane Cell Surface Membrane
	Molecular Function	Cytokine Activity	Cytokine Receptor Activity Protein Binding Interleukin-17 Receptor Activity
	Biological Process	Inflammatory Response Immune Response Signal Transduction Cell-cell Signaling Positive Regulation Of Cytokine Production Involved In Inflammatory Response	Regulation Of Cell Growth Defense Response Cytokine-mediated Signaling Pathway Positive Regulation Of Interleukin-13 Production Positive Regulation Of Interleukin-5 Production Positive Regulation Of Inflammatory Response
Pathways			Interleukin-17 signaling
Drugs
Diseases
GWAS		Antipsychotic drug-induced weight gain in schizophrenia ( 31447353) Serum bilirubin levels x Mediterranean diet adherence interaction in metabolic syndrome ( 30621171)	Axial length ( 24144296) Body mass index ( 26426971) interleukin 17 receptor B levels ( 25147954) Refractive error ( 32231278) Response to tofacitinib treatment (herpes zoster) ( 33455090) Response to tofacitinib treatment (herpes zoster)(time to event) ( 33455090) Response to tofacitinib treatment in rheumatoid arthritis (herpes zoster) ( 33455090) Response to tofacitinib treatment in rheumatoid arthritis (herpes zoster)(time to event) ( 33455090)
Interacting Genes		2 interacting genes: ENO2 IL17RB	4 interacting genes: IL17B IL25 RPS6KA5 TRAF6
Entrez ID		27190	55540
HPRD ID		05217	05677
Ensembl ID		ENSG00000127743	ENSG00000056736
Uniprot IDs		Q9UHF5	Q9NRM6
PDB IDs			7UWJ 7UWK 7UWL
Enriched GO Terms of Interacting Partners?		Phosphopyruvate Hydratase Complex Phosphopyruvate Hydratase Activity Interleukin-17 Receptor Activity Glycolytic Process Through Glucose-6-phosphate Cell Surface Glycolytic Process Through Fructose-6-phosphate Canonical Glycolysis Regulation Of Interleukin-5 Production Positive Regulation Of Interleukin-5 Production Positive Regulation Of Interleukin-13 Production ADP Catabolic Process Gluconeogenesis ADP Metabolic Process Purine Ribonucleoside Diphosphate Catabolic Process Nucleoside Diphosphate Catabolic Process Glycolytic Process Hexose Biosynthetic Process Glucose Catabolic Process Photoreceptor Inner Segment Ribonucleoside Diphosphate Catabolic Process Cytokine Receptor Activity Pyruvate Metabolic Process Synaptic Membrane Purine Ribonucleotide Catabolic Process Ribonucleoside Diphosphate Metabolic Process Purine Nucleotide Catabolic Process Nucleoside Diphosphate Metabolic Process Response To Estradiol Nicotinamide Nucleotide Metabolic Process Nucleotide Catabolic Process Carbohydrate Biosynthetic Process Carbohydrate Catabolic Process Glucose Metabolic Process Nucleoside Phosphate Catabolic Process Growth Cone Perikaryon	Interleukin-1-mediated Signaling Pathway Defense Response Positive Regulation Of NF-kappaB Transcription Factor Activity Inflammatory Response Positive Regulation Of DNA-binding Transcription Factor Activity Histone H2AS1 Kinase Activity Interleukin-17E Receptor Binding Myeloid Leukocyte Differentiation Regulation Of Cytokine Production Positive Regulation Of Macromolecule Biosynthetic Process Histone H3S28 Kinase Activity Positive Regulation Of Biosynthetic Process Regulation Of DNA-binding Transcription Factor Activity Histone H3S10 Kinase Activity Cytokine Activity Positive Regulation Of Macromolecule Metabolic Process Response To Stress Immune Response Interleukin-17A-mediated Signaling Pathway Myeloid Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Eosinophil Differentiation Positive Regulation Of Metabolic Process CD40 Signaling Pathway Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway CD40 Receptor Complex TRIF-dependent Toll-like Receptor Signaling Pathway Protein Kinase B Binding Interleukin-33-mediated Signaling Pathway T-helper 1 Type Immune Response Interleukin-17-mediated Signaling Pathway Positive Regulation Of CREB Transcription Factor Activity Response To Nematode Positive Regulation Of JUN Kinase Activity Leukocyte Differentiation Cytokine-mediated Signaling Pathway Positive Regulation Of RNA Biosynthetic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of DNA-templated Transcription Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane MyD88-dependent Toll-like Receptor Signaling Pathway Ubiquitin-ubiquitin Ligase Activity Signal Transduction Bone Remodeling Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Myeloid Dendritic Cell Differentiation Stimulatory C-type Lectin Receptor Signaling Pathway Positive Regulation Of RNA Metabolic Process Protein Branched Polyubiquitination
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