SLC39A1 and KCNAB2

Number of citations of the paper that reports this interaction (PubMedID 10477520)
0

Data Source:
HPRD (two hybrid)

		SLC39A1	KCNAB2
Description		solute carrier family 39 member 1	potassium voltage-gated channel subfamily A regulatory beta subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane	Cytoplasm Cytosol Cytoskeleton Microtubule Plasma Membrane Voltage-gated Potassium Channel Complex Cytoplasmic Side Of Plasma Membrane Membrane Axon Specific Granule Membrane Cell Projection Neuron Projection Juxtaparanode Region Of Axon Synapse Tertiary Granule Membrane Pinceau Fiber
	Molecular Function	Signaling Receptor Binding Zinc Ion Transmembrane Transporter Activity Protein Binding Inorganic Cation Transmembrane Transporter Activity Metal Ion Transmembrane Transporter Activity	Voltage-gated Potassium Channel Activity Protein Binding Alcohol Dehydrogenase (NADP+) Activity Potassium Channel Regulator Activity Oxidoreductase Activity Transmembrane Transporter Binding Methylglyoxal Reductase (NADPH) (acetol Producing) Activity
	Biological Process	In Utero Embryonic Development Monoatomic Ion Transport Monoatomic Cation Transport Zinc Ion Transport Metal Ion Transport Embryonic Cranial Skeleton Morphogenesis Transmembrane Transport Limb Development Zinc Ion Transmembrane Transport	Monoatomic Ion Transport Potassium Ion Transport Potassium Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport Regulation Of Protein Localization To Cell Surface
Pathways		Zinc influx into cells by the SLC39 gene family	Voltage gated Potassium channels Neutrophil degranulation
Drugs			Enflurane Promethazine Miconazole
Diseases
GWAS		Age at first birth ( 27798627) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Empathy quotient ( 29527006) Fish- and plant-related diet ( 32066663) Fruit consumption ( 32066663) Lentiform nucleus volume ( 22903471) Raw vegetable consumption ( 32066663) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Metabolite levels ( 23823483)
Interacting Genes		16 interacting genes: CERS2 COMT CXCL16 CXCL9 CYB561 HTR2C HTR4 KCNAB1 KCNAB2 NOTCH3 PLEKHM2 PRKCZ SHB SLC39A2 TRARG1 YIPF6	12 interacting genes: ATXN1 CD4 CEBPA FAM3B KCNA2 LCOR NEDD4 NEDD4L SLC39A1 SLC39A2 SQSTM1 TNFRSF18
Entrez ID		27173	8514
HPRD ID		11984	03090
Ensembl ID		ENSG00000143570	ENSG00000069424
Uniprot IDs		A0A0A0MTL8 Q9NY26	B2R776 Q13303
PDB IDs			1ZSX 7EJ1 7EJ2 7WF3 7WF4
Enriched GO Terms of Interacting Partners?		Membrane Serotonin Binding Serotonin Receptor Activity Serotonin Receptor Signaling Pathway Juxtaparanode Region Of Axon Alcohol Dehydrogenase (NADP+) Activity G Protein-coupled Serotonin Receptor Activity Neurotransmitter Receptor Activity G Protein-coupled Serotonin Receptor Signaling Pathway Regulation Of Appetite Positive Regulation Of T-helper Cell Differentiation Behavioral Fear Response Behavioral Defense Response Plasma Membrane Norepinephrine Secretion Fear Response Catechol O-methyltransferase Activity Large Intestinal Transit Chemokine Activity Positive Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation Potassium Channel Regulator Activity Pinceau Fiber Negative Regulation Of Schwann Cell Proliferation Involved In Axon Regeneration Regulation Of T-helper Cell Differentiation G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Voltage-gated Potassium Channel Activity Positive Regulation Of Alpha-beta T Cell Differentiation Cellular Response To Phosphate Starvation Cell-cell Signaling Cell Communication Response To Peptide Hormone Multicellular Organismal Response To Stress Signaling Digestive System Process Chemical Synaptic Transmission Ascorbate Homeostasis Gq/11-coupled Serotonin Receptor Activity Positive Regulation Of Phosphatidylinositol Biosynthetic Process 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine Binding Monoatomic Cation Transmembrane Transport Metal Ion Transport Inorganic Cation Transmembrane Transport Transmembrane Transport Regulation Of Cell Differentiation Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of CD4-positive, Alpha-beta T Cell Activation Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Alpha-beta T Cell Activation	Fat Cell Proliferation Sodium Channel Inhibitor Activity Negative Regulation Of Potassium Ion Export Across Plasma Membrane Potassium Channel Inhibitor Activity Metal Ion Transport Regulation Of Potassium Ion Export Across Plasma Membrane Negative Regulation Of Sodium Ion Transport Monoatomic Cation Transport Receptor Catabolic Process Negative Regulation Of Potassium Ion Transmembrane Transport Metal Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transporter Activity Positive Regulation Of Protein Metabolic Process DNA-templated Transcription Zinc Ion Transport Zinc Ion Transmembrane Transport Regulation Of Membrane Potential Ionotropic Glutamate Receptor Binding Negative Regulation Of Potassium Ion Transport Monoatomic Ion Transport Regulation Of Protein Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Neuromuscular Junction Development Positive Regulation Of Protein Catabolic Process Macrophage Differentiation Positive Regulation Of Catabolic Process Receptor Metabolic Process Interleukin-16 Binding Regulation Of Biological Quality Interleukin-16 Receptor Activity Helper T Cell Enhancement Of Adaptive Immune Response Regulation Of Monoatomic Cation Transmembrane Transport RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Monoatomic Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Protein Targeting To Vacuole Protein Monoubiquitination Formation Of Structure Involved In A Symbiotic Process Protein Polyubiquitination Regulation Of Dendrite Morphogenesis Establishment Of Protein Localization To Vacuole Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Potassium Ion Transmembrane Transport Transcription By RNA Polymerase II Inorganic Ion Transmembrane Transport Energy Homeostasis Negative Regulation Of Cation Transmembrane Transport Regulation Of Sodium Ion Transport Receptor Internalization Response To Methamphetamine Hydrochloride
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