NDOR1 and PMPCA

		NDOR1	PMPCA
Description		NADPH dependent diflavin oxidoreductase 1	peptidase, mitochondrial processing subunit alpha
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Intermediate Filament Cytoskeleton Perinuclear Region Of Cytoplasm	Extracellular Space Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Mitochondrial Processing Peptidase Complex
	Molecular Function	NADPH-hemoprotein Reductase Activity Protein Binding Electron Transfer Activity FMN Binding Oxidoreductase Activity Oxidoreductase Activity, Acting On NAD(P)H Oxidoreductase Activity, Acting On NAD(P)H, Heme Protein As Acceptor Flavin Adenine Dinucleotide Binding NADP Binding NADPH Binding FAD Binding NADPH-iron-sulfur [2Fe-2S] Protein Oxidoreductase Activity	Metalloendopeptidase Activity Protein Binding Metal Ion Binding
	Biological Process	Iron-sulfur Cluster Assembly Electron Transport Chain	Proteolysis Protein Processing Involved In Protein Targeting To Mitochondrion Protein Processing
Pathways		Cytosolic iron-sulfur cluster assembly	Mitochondrial protein import Processing of SMDT1 Mitochondrial protein degradation
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31152163) High light scatter reticulocyte count ( 27863252 32888494) High light scatter reticulocyte percentage of red cells ( 27863252 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular hemoglobin concentration ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494) Reticulocyte count ( 27863252 32888494) Reticulocyte fraction of red cells ( 27863252 32888494)	Apolipoprotein B levels ( 32203549) Chronotype ( 30696823) Crohn's disease ( 28067908) Granulocyte count ( 27863252) Inflammatory bowel disease ( 23128233 28067908) Joint damage in rheumatoid arthritis ( 26498133) LDL cholesterol levels ( 32203549) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Serum total protein levels ( 29403010) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Ulcerative colitis ( 28067908) White blood cell count ( 27863252)
Interacting Genes		30 interacting genes: C7orf57 CCDC33 CENATAC CYCS DLG4 DRC4 EFHC2 ENOX2 GPS2 HOXB2 KIAA0408 LMO2 LMO3 LNX1 MEOX1 MTUS2 NAB2 NLK PMPCA PSMB6 TCF4 TCHP TEPSIN TLE5 UBQLN1 UBQLN2 ZBTB42 ZC2HC1C ZNF620 ZNF774	16 interacting genes: ASS1 AVEN BMPR2 KIF2C LINC01554 NDOR1 NPSR1 NSMF OGT OLFM1 PCDHB4 PMPCB SCUBE1 SKIC2 UBAC1 ZNF76
Entrez ID		27158	23203
HPRD ID		10444	07500
Ensembl ID		ENSG00000188566	ENSG00000165688
Uniprot IDs		Q9UHB4	Q10713 Q5SXN9
PDB IDs		4H2D
Enriched GO Terms of Interacting Partners?			Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Regulation Of Receptor Localization To Synapse Regulation Of Protein Localization To Synapse
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