FOXP1 and BAZ2B

Number of citations of the paper that reports this interaction (PubMedID 31623628)
49

Data Source:
BioGRID (unspecified method)

		FOXP1	BAZ2B
Description		forkhead box P1	bromodomain adjacent to zinc finger domain 2B
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Core Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding Sequence-specific DNA Binding Metal Ion Binding Nuclear Androgen Receptor Binding Sequence-specific Double-stranded DNA Binding	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of B Cell Apoptotic Process Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II DNA Damage Response Regulation Of Gene Expression Positive Regulation Of Endothelial Cell Migration Negative Regulation Of Gene Expression Striatum Development Osteoclast Differentiation Forebrain Development Response To Lipopolysaccharide Regulation Of Interleukin-1 Beta Production Regulation Of Interleukin-12 Production Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Interleukin-21 Production Response To Testosterone Osteoclast Development Macrophage Activation Monocyte Activation Endothelial Cell Activation Regulation Of Monocyte Differentiation Negative Regulation Of DNA-templated Transcription Animal Organ Development Positive Regulation Of Smooth Muscle Cell Proliferation Regulation Of Inflammatory Response Positive Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development T Follicular Helper Cell Differentiation Cellular Response To Tumor Necrosis Factor Regulation Of Defense Response To Bacterium Regulation Of Macrophage Colony-stimulating Factor Production Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Regulation Of Endothelial Tube Morphogenesis Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Adventurousness ( 30643258) Age at first sexual intercourse ( 34211149) Anorexia nervosa ( 31308545) Apolipoprotein A1 levels ( 32203549) Arthritis (juvenile idiopathic) ( 33106285) Asthma ( 32296059) Attention deficit hyperactivity disorder ( 18821565) Autism spectrum disorder or schizophrenia ( 28540026) Automobile speeding propensity ( 30643258) Barrett's esophagus ( 24121790) Barrett's esophagus or Esophageal adenocarcinoma ( 31527586 27527254) Basal cell carcinoma ( 31174203 33549134 27539887) Beef consumption ( 32066663) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Breast cancer ( 29059683) Childhood maltreatment ( 32066696) Chronotype ( 30696823) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Cutaneous squamous cell carcinoma ( 32041948) Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined) ( 24121790) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Eosinophil percentage of white cells ( 32888494) Esophageal adenocarcinoma ( 24121790) Familial lung adenocarcinoma ( 29924316) FEV1 ( 30804560) Gastroesophageal reflux disease ( 31527586) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Haemorrhoidal disease ( 33888516) Hand grip strength ( 29691431) Height ( 28552196) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Household income (MTAG) ( 31844048) Inflammatory bowel disease ( 28067908) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 29617998 24002674 31798171) Intraocular pressure and central corneal thickness (multi-trait analysis) ( 31798171) Keratinocyte cancer (MTAG) ( 31174203) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Lung function (FVC) ( 30804560) Lymphocyte count ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244 24076602) Nasal polyps ( 30643255) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 27863252 32888494) Non-melanoma skin cancer ( 29739929) Nose size ( 27182965) Number of sexual partners ( 30643258) Oily fish consumption ( 32066663) Optic disc size ( 31809533) Pork consumption ( 32066663) PR interval ( 32439900) Primary sclerosing cholangitis ( 27992413) Prudent dietary pattern ( 28644415) Pulse pressure ( 27841878) Red blood cell count ( 27863252 32888494) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Schizophrenia ( 30285260) Selective IgA deficiency ( 27723758) Smoking initiation ( 33082346) Squamous cell carcinoma ( 26829030) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Subcutaneous adipose tissue ( 22589738) Systolic blood pressure ( 27841878) Tooth agenesis (maxillary lateral incisors) ( 29364747) Vitiligo ( 27723757) Waist-to-hip ratio adjusted for BMI ( 34021172) Walking pace ( 33128006) White blood cell count ( 32888494)	Femur bone mineral density x serum urate levels interaction ( 34046847) Ferritin levels ( 33491795) Major depressive episode treated with electroconvulsive therapy ( 33483693) Monocyte count ( 32888494) Neutrophil percentage of white cells ( 32888494) Night sleep phenotypes ( 27126917) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Refractive error ( 32231278) Sudden cardiac arrest ( 21738491) Tourette syndrome ( 30818990)
Interacting Genes		117 interacting genes: AKR1A1 ALB ALYREF ANLN ANXA2 AURKA BAZ2B C1QBP CCDC167 CCDC73 CDKN2AIP CHSY1 CPSF6 CSDE1 CTBP1 DCD DDX17 DDX19B DLAT DMD DOC2A ECE2 EXOG FOXP2 FOXP4 GAPDH GAR1 GOLGA2 H1-4 H2AC25 HERC1 HNRNPD HNRNPH1 HNRNPK HNRNPUL1 HSPA8 HSPB1 HYDIN IGF2BP3 IKZF1 IL3RA IQSEC2 KIF27 LRRK1 MNAT1 MTUS1 MYH7B NCOR2 NLRC4 NR2F1 NR2F2 PARN PCBP2 PCSK4 PKD1P6 POP7 PTBP1 PURA RAG2 RAN RBMS2 RBMX RGL1 RPL22 RPL23A RPL27 RPL28 RPL31 RPL35 RPL37A RPL4 RPL5 RPL6 RPS15A RPS16 RPS20 RPS27A RPS3 RUVBL1 SATB1 SATB2 SLC22A16 SMARCA2 SNRPA1 SNRPB2 SNRPC SNRPD1 SNRPD2 SNRPE SNRPF SNRPN SOX5 SRP14 SRSF1 SRSF3 SRSF8 SSBP1 STAU1 STAU2 STRAP TARBP2 TBC1D23 THUMPD1 TNFRSF1B TRA2A TUBA1B TUBA8 TYW1B UGGT1 UMPS WBP11 WDR11 WDR72 YY1 ZC3HAV1 ZDHHC16 ZMYM2	21 interacting genes: APIP BCL2L13 BIVM CEP70 CTBP2 FOXP1 FXR2 GOLGA2 HMBOX1 HSF2BP PRNP RASGEF1B RNF10 SCN2A SEPTIN2 STAC3 TFIP11 TRAF2 TRIM23 ZBTB14 ZBTB8A
Entrez ID		27086	29994
HPRD ID		18518	09295
Ensembl ID		ENSG00000114861	ENSG00000123636
Uniprot IDs		A0A0B4J2F3 A0A3B3IRW5 A0A3B3IST0 A0A3B3IT66 Q548T7 Q8N2P0 Q8TEA2 Q9H334	Q9UIF8
PDB IDs		2KIU	2E7O 3G0L 3Q2F 4CUP 4CUQ 4CUR 4CUS 4CUT 4CUU 4IR3 4IR4 4IR5 4IR6 4NR9 4NRA 4NRB 4NRC 4QC1 4QC3 4QF3 4RVR 4XUA 4XUB 5CQ3 5CQ4 5CQ5 5CQ6 5CQ7 5CQ8 5CQA 5CU8 5CUA 5CUB 5CUC 5CUD 5CUE 5CUG 5DYU 5DYX 5E73 5E74 5E9I 5E9K 5E9L 5E9M 5E9Y 5L8T 5L8U 5L96 5L97 5L98 5L99 5MGE 5MGF 5MGG 5OR9 5ORB 5PB7 5PB8 5PB9 5PBA 5PBB 5PBC 5PBD 5PBE 5PBF 5PBG 5PBH 5PBI 5PBJ 5PBK 5PBL 5PBM 5PBN 5PBO 5PBP 5PBQ 5PBR 5PBS 5PBT 5PBU 5PBV 5PBW 5PBX 5PBY 5PBZ 5PC0 5PC1 5PC2 5PC3 5PC4 5PC5 5PC6 5PC7 5PC8 5PC9 5PCA 5PCB 5PCC 5PCD 5PCE 5PCF 5PCG 5PCH 5PCI 5PCJ 5PCK 5PCL 5PCM 5PCN 5PCO 5PCP 5PCQ 5PCR 5PCS 5PCT 5PCU 5PCV 5PCW 5PCX 5PCZ 5PD0 5PD1 5PD2 5PD3 5PD4 5PD5 5PD6 5PD7 5PD8 5PD9 5PDA 5PDB 5PDC 5PDD 5PDE 5PDF 5PDG 5PDH 5PDI 5PDJ 5PDK 5PDL 5PDM 5PDN 5PDO 5PDP 5PDQ 5PDR 5PDS 5PDT 5PDU 5PDV 5PDW 5PDX 5PDY 5PDZ 5PE0 5PE1 5PE2 5PE3 5PE4 5PE5 5PE6 5PE7 5PE8 5PE9 5PEA 5PEB 5PEC 5PED 5PEE 5PEF 5PEG 5PEH 5PEI 5PEJ 5PEK 5PEL 5PEM 5PEN 5PEO 5PEQ 5PER 5PES 5PET 5PEU 5PEV 5PEW 5PEX 5PEY 5PEZ 5PF0 5PF1 5PF2 5PF3 5PF4 5PF5 5PF6 5PF7 5PF8 5PF9 5PFA 5PFB 5PFC 5PFD 5PFE 5PFF 5PFG 5PFH 5PFI 5PFJ 5PFL 5PFM 5PFN 5PFO 5PFP 5PFQ 5PFR 5PFS 5PFT 5PFU 5PFV 5PFW 5PFX 5PFY 5PFZ 5PG0 5PG1 5PG2 5PG3 5PG4 5PG5 5PG6 5PG7 5PG8 5PG9 5PGA 5PGB 5PGC 5PGD 5PGE 5PGF 5PGG 5PGH 5PGI 5PGJ 5PGK 5PGL 5PGN 5PGO 5PGP 5PGQ 5PGR 5PGS 5PGT 6FGT 6FGU 6FH6 6FH7 6FHQ 6FI1 7Q42 7WIN
Enriched GO Terms of Interacting Partners?		RNA Binding Ribonucleoprotein Complex RNA Processing Cytosolic Ribosome RNA Splicing MRNA Metabolic Process MRNA Binding Nucleic Acid Metabolic Process MRNA Processing Cytoplasmic Translation RNA Metabolic Process Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome Macromolecule Metabolic Process RNA Splicing, Via Transesterification Reactions Structural Constituent Of Ribosome Catalytic Step 2 Spliceosome Nucleus Spliceosomal Complex Ribosome Cytosolic Large Ribosomal Subunit U1 SnRNP Nucleic Acid Binding U2 SnRNP Small Nuclear Ribonucleoprotein Complex Translation U4 SnRNP Protein-RNA Complex Assembly U2-type Prespliceosome Assembly Nucleoplasm PICln-Sm Protein Complex U2-type Spliceosomal Complex U2-type Catalytic Step 2 Spliceosome Regulation Of MRNA Splicing, Via Spliceosome SMN-Sm Protein Complex 7-methylguanosine Cap Hypermethylation U5 SnRNP Macromolecule Biosynthetic Process Regulation Of MRNA Processing Regulation Of MRNA Metabolic Process Spliceosomal SnRNP Assembly Negative Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing Spliceosomal Complex Assembly Methylosome U2-type Precatalytic Spliceosome Nucleolus Extracellular Exosome Cytosolic Small Ribosomal Subunit Focal Adhesion	Identical Protein Binding
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