AKAP8L and PCDHB14

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AKAP8L	PCDHB14
Description		A-kinase anchoring protein 8 like	protocadherin beta 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Nuclear Matrix PML Body Nuclear Speck Ribonucleoprotein Complex	Plasma Membrane Membrane Synapse
	Molecular Function	DNA Binding RNA Binding Protein Binding Lamin Binding Zinc Ion Binding DEAD/H-box RNA Helicase Binding Protein Kinase A Regulatory Subunit Binding Histone Deacetylase Binding Metal Ion Binding	Calcium Ion Binding Protein Binding Cell Adhesion Molecule Binding
	Biological Process	MRNA Processing Mitotic Chromosome Condensation RNA Splicing Regulation Of MRNA Export From Nucleus Cell Cycle G2/M Phase Transition Positive Regulation Of Transcription By RNA Polymerase II Nuclear Membrane Disassembly	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Chemical Synaptic Transmission Nervous System Development Synapse Assembly Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules
Pathways		Formation of WDR5-containing histone-modifying complexes
Drugs
Diseases
GWAS		Red blood cell count ( 32888494)
Interacting Genes		70 interacting genes: ABI2 ACTN2 AP1M1 ASF1B ATOSB ATPAF2 BEX3 BRME1 CARHSP1 CATSPER1 CCDC120 CCDC24 CDC6 CNNM3 CREB5 CSTF2 CSTF2T DGCR6 DHX9 DMRT3 DSCR9 EMD ENKD1 EPHX3 FOXD4 GPANK1 GPS2 HEMK1 HGS HSF4 HUNK ICAM4 IL18R1 INCA1 KPRP LAGE3 LBR MYOZ1 MYPOP OR7A17 PATZ1 PCDHB14 PEF1 PITX1 PLEKHN1 PRKAA2 PRKACA PRPF40A PTP4A2 RAMAC RASAL3 RTP5 RUSC1 SAMD4A SAXO1 SAXO4 SH3RF2 SNRPC TEKT4 TEKT5 TENT5B TFAP2D TIAL1 TLE5 TMPO TMSB4X TRIB3 TSGA10IP WDR25 ZNF366	17 interacting genes: AKAP8L CDK12 GOLGA6L9 HNRNPK HNRNPR KHDRBS3 KRT27 KRTAP6-3 MTUS2 PSTPIP1 PURB RBMX RBMY1A1 RBMY1F RBMY1J SRSF3 TRA2B
Entrez ID		26993	56122
HPRD ID		10641	06958
Ensembl ID		ENSG00000011243	ENSG00000120327
Uniprot IDs		Q9ULX6	Q9Y5E9
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Sperm Flagellum	MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome RNA Splicing Regulation Of MRNA Processing MRNA Metabolic Process Regulation Of RNA Splicing RNA Processing MRNA Binding Positive Regulation Of MRNA Splicing, Via Spliceosome Spliceosomal Complex Regulation Of MRNA Metabolic Process Positive Regulation Of RNA Splicing Nucleic Acid Binding Regulation Of Alternative MRNA Splicing, Via Spliceosome RNA Metabolic Process RNA Binding Positive Regulation Of MRNA Metabolic Process Nucleic Acid Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome Nucleoplasm RNA Splicing, Via Transesterification Reactions Protein Domain Specific Binding Regulation Of RNA Metabolic Process Catalytic Step 2 Spliceosome Pre-mRNA Binding Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Splicing Positive Regulation Of Biosynthetic Process Ribonucleoprotein Complex Identical Protein Binding Nucleus Positive Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Macromolecule Metabolic Process Protein-RNA Sequence-specific Adaptor Activity Cyclin K-CDK12 Complex Regulation Of Primary Metabolic Process Positive Regulation Of Metabolic Process Supraspliceosomal Complex Nuclear Cyclin-dependent Protein Kinase Holoenzyme Complex Positive Regulation Of Low-density Lipoprotein Particle Clearance Purine-rich Negative Regulatory Element Binding Negative Regulation Of MRNA Metabolic Process Regulation Of Macromolecule Metabolic Process
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