AATF and MYO1D

Data Source:
BioGRID (affinity chromatography technology)

		AATF	MYO1D
Description		apoptosis antagonizing transcription factor	myosin ID
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Nucleolus Cytoplasm Golgi Apparatus	Cytoplasm Endosome Early Endosome Smooth Endoplasmic Reticulum Cytosol Plasma Membrane Microvillus Brush Border Cell Cortex Actin Cytoskeleton Basolateral Plasma Membrane Myosin Complex Axon Axolemma Cytoplasmic Vesicle Vesicle Neuron Projection Neuronal Cell Body Perikaryon Myelin Sheath Plasma Membrane Raft Extracellular Exosome Apical Dendrite
	Molecular Function	RNA Binding Protein Binding Protein Kinase Binding Leucine Zipper Domain Binding Tau Protein Binding	Microfilament Motor Activity Calmodulin Binding ATP Binding Protein Domain Specific Binding Actin-dependent ATPase Activity Calcium-dependent Protein Binding Actin Filament Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Cell Adhesion Regulation Of Mitotic Cell Cycle Negative Regulation Of Superoxide Anion Generation Embryonic Cleavage Ribosome Biogenesis Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process Negative Regulation Of Apoptotic Process Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Apoptotic Signaling Pathway	Actin Filament Organization Negative Regulation Of Phosphatase Activity Protein Transport Vesicle Transport Along Actin Filament Forebrain Development Cellular Localization Early Endosome To Recycling Endosome Transport
Pathways		NRAGE signals death through JNK
Drugs
Diseases
GWAS		Body mass index ( 26426971) Erectile dysfunction ( 30583798) Obesity-related traits ( 23251661) Thyroid volume in Hashimotoâ€™s thyroiditis ( 32019955)	Emotional recognition ( 32366958) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Hypertension risk in short sleep duration ( 22322875) Immature fraction of reticulocytes ( 32888494 27863252) Local histogram emphysema pattern ( 25006744) Myopia ( 27182965) Neurofibrillary tangles ( 25188341) Pancreatic cancer ( 20686608) Red cell distribution width ( 32888494 27863252) Refractive error ( 23396134 32231278) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Spherical equivalent or myopia (age of diagnosis) ( 29808027)
Interacting Genes		28 interacting genes: ATM ATR AURKA CHEK1 CHEK2 CPD DAPK3 DAZAP2 EFNB3 FBXO7 HIPK2 LDOC1 LZTR1 MAPT MPHOSPH6 NEDD4L NGDN PALS2 PAWR PCBD2 POLR2J RB1 RELA SMAD3 SP1 SS18L1 TSG101 ZNF468	1 interacting genes: PTEN
Entrez ID		26574	4642
HPRD ID		12236	07581
Ensembl ID		ENSG00000275700	ENSG00000176658
Uniprot IDs		Q9NY61	J3KRL0 J3QRN6 O94832 Q8N618
PDB IDs		5W6A
Enriched GO Terms of Interacting Partners?
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