GCNT1 and CSDE1

		GCNT1	CSDE1
Description		glucosaminyl (N-acetyl) transferase 1	cold shock domain containing E1
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Space Golgi Apparatus Trans-Golgi Network Membrane Golgi Cisterna	P-body Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Cytoplasmic Stress Granule CRD-mediated MRNA Stability Complex MCRD-mediated MRNA Stability Complex
	Molecular Function	Beta-1,3-galactosyl-O-glycosyl-glycoprotein Beta-1,6-N-acetylglucosaminyltransferase Activity Protein Binding UDP-glycosyltransferase Activity Transferase Activity Glycosyltransferase Activity	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding RNA Stem-loop Binding LncRNA Binding RISC Complex Binding
	Biological Process	Protein Glycosylation Glycoprotein Biosynthetic Process Protein O-linked Glycosylation Via N-acetyl-galactosamine Response To Insulin Tissue Morphogenesis Leukocyte Tethering Or Rolling Cell Adhesion Molecule Production Kidney Morphogenesis Positive Regulation Of Leukocyte Tethering Or Rolling	Regulation Of Translational Initiation Male Gonad Development Stress Granule Assembly Positive Regulation Of Translation ERK1 And ERK2 Cascade CRD-mediated MRNA Stabilization Nuclear-transcribed MRNA Catabolic Process, No-go Decay IRES-dependent Viral Translational Initiation Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of Cytoplasmic Translation
Pathways		O-linked glycosylation of mucins
Drugs
Diseases
GWAS		Acute graft versus host disease in bone marrow transplantation (recipient effect) ( 27595289) D-dimer levels in HIV infection ( 33095540) Dialysis-related mortality ( 21546767) Monocyte count ( 32888494) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)	Autism ( 24189344)
Interacting Genes		4 interacting genes: CSDE1 GOLPH3 GOLPH3L PRKCB	31 interacting genes: ARHGAP5 C11orf68 CDC7 CEBPA CTBS DOK1 DPYD ERBB2 FAM9B FOXP1 GCKR GCNT1 GFI1 HID1 HNRNPD IGFBP5 KCNMB4 NEIL3 PABPC1 PCSK7 PSMG1 RNF10 SH3GLB1 SLIT2 SNRPB2 SNW1 STT3A SYNCRIP WBP4 WFS1 WNK1
Entrez ID		2650	7812
HPRD ID		02669	15949
Ensembl ID		ENSG00000187210	ENSG00000009307
Uniprot IDs		Q02742	O75534
PDB IDs			1WFQ 1X65 2YTV 2YTX 2YTY
Enriched GO Terms of Interacting Partners?		Golgi Vesicle Budding Cargo Adaptor Activity Protein Targeting To Golgi Apparatus Golgi Cisterna Positive Regulation Of Protein Secretion Positive Regulation Of Protein Transport Regulation Of Protein Secretion Positive Regulation Of Secretion Positive Regulation Of Secretion By Cell Positive Regulation Of Establishment Of Protein Localization Golgi To Plasma Membrane Protein Transport Phosphatidylinositol-4-phosphate Binding Vesicle Budding From Membrane Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Positive Regulation Of Protein Localization Regulation Of Protein Transport Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Golgi Cisterna Membrane Regulation Of Establishment Of Protein Localization Regulation Of Secretion By Cell Regulation Of Secretion Membrane Organization Post-Golgi Vesicle-mediated Transport Golgi Organization Vesicle-mediated Transport To The Plasma Membrane Positive Regulation Of Transport Histone H3T6 Kinase Activity Asymmetric Golgi Ribbon Formation Regulation Of Protein Localization Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Trans-Golgi Network Cell Adhesion Molecule Production Cellular Response To Rapamycin Protein Localization To Plasma Membrane Protein Targeting Establishment Of Protein Localization To Membrane Protein Transport Protein Kinase C Signaling Protein Retention In Golgi Apparatus Protein Localization To Cell Periphery MCRD-mediated MRNA Stability Complex RISC Complex Binding Nuclear-transcribed MRNA Catabolic Process, No-go Decay CRD-mediated MRNA Stability Complex Response To Rapamycin Establishment Of Protein Localization Golgi Vesicle Transport Golgi Apparatus Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway	MCRD-mediated MRNA Stability Complex CRD-mediated MRNA Stabilization Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of Cytoplasmic Translation Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Spliceosomal Complex Catalytic Step 2 Spliceosome Macromolecule Metabolic Process MRNA Splicing, Via Spliceosome Regulation Of Cytoplasmic Translation RNA Splicing, Via Transesterification Reactions Regulation Of Translation Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Positive Regulation Of Translation MRNA Stabilization Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Carbohydrate Homeostasis Glucose Homeostasis Negative Regulation Of MRNA Catabolic Process RNA Stabilization Nucleic Acid Binding RNA Splicing Proteasome Binding Response To Ketone Post-transcriptional Regulation Of Gene Expression Negative Regulation Of RNA Catabolic Process Negative Regulation Of MRNA Metabolic Process Motor Neuron Axon Guidance Nuclear Androgen Receptor Binding MRNA Processing Regulation Of Protein Metabolic Process Regulation Of Biological Quality Nuclear Matrix Cellular Response To Stress RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Uracil Binding Beta-alanine Metabolic Process Thymidine Catabolic Process Beta-alanine Biosynthetic Process Dihydropyrimidine Dehydrogenase (NADP+) Activity Hepatocyte Dedifferentiation Cellular Response To Putrescine Negative Regulation Of Smooth Muscle Cell Migration Negative Regulation Of Skeletal Muscle Hypertrophy U2-type Catalytic Step 2 Spliceosome Proteasome Core Complex Assembly Induction Of Negative Chemotaxis Corticospinal Neuron Axon Guidance Through Spinal Cord Protein Localization To Vacuolar Membrane MCM Complex Binding
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