POLDIP2 and POLN

Number of citations of the paper that reports this interaction (PubMedID 20554254)
0

Data Source:
BioGRID (two hybrid)

		POLDIP2	POLN
Description		DNA polymerase delta interacting protein 2	DNA polymerase nu
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GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Matrix Cell-cell Junction Midbody Mitochondrial Nucleoid Mitotic Spindle	Nucleus Nucleoplasm Nucleolus
	Molecular Function	DNA Binding Protein Binding	Nucleic Acid Binding DNA Binding DNA-directed DNA Polymerase Activity Protein Binding Transferase Activity Nucleotidyltransferase Activity Cyclin Binding DNA Polymerase Activity
	Biological Process	DNA Repair DNA Damage Response Mitochondrion Organization Negative Regulation Of Macroautophagy Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Focal Adhesion Assembly Error-free Translesion Synthesis Mitotic Spindle Assembly Positive Regulation Of Mitotic Cytokinesis Vascular Associated Smooth Muscle Cell Proliferation	Double-strand Break Repair Via Homologous Recombination DNA Synthesis Involved In DNA Repair DNA Replication DNA-templated DNA Replication DNA Repair Double-strand Break Repair DNA Damage Response Translesion Synthesis Interstrand Cross-link Repair
Pathways			Fanconi Anemia Pathway
Drugs
Diseases
GWAS		Osteoprotegerin levels ( 25080503)	Alzheimer's disease ( 22159054) Diastolic blood pressure ( 30224653) Diffusing capacity of carbon monoxide ( 30694715) Height ( 31562340)
Interacting Genes		20 interacting genes: AGTRAP ALAS1 APP ASCC2 CPE DNAAF6 DSCAM FBXO7 HDAC6 MAD2L2 MTUS2 PCNA PDPK1 POLD2 POLN PTEN REV1 SELENBP1 TAB1 TMEM97	2 interacting genes: ATR POLDIP2
Entrez ID		26073	353497
HPRD ID		17874	17876
Ensembl ID		ENSG00000004142	ENSG00000130997
Uniprot IDs		B4DEM9 Q9Y2S7	Q7Z5Q5
PDB IDs		6Z9C 6ZLX	4XVI 4XVK 4XVL 4XVM
Enriched GO Terms of Interacting Partners?		Translesion Synthesis Postreplication Repair DNA Synthesis Involved In DNA Repair DNA Biosynthetic Process Error-prone Translesion Synthesis DNA Replication Zeta DNA Polymerase Complex Neuron Projection Organization DNA Repair Response To Stress Regulation Of Growth DNA Strand Elongation Involved In DNA Replication DNA Metabolic Process Regulation Of Axon Extension Involved In Axon Guidance Collateral Sprouting Neuron Projection Morphogenesis DNA Strand Elongation DNA Damage Response Cellular Response To Stress Dendritic Spine Morphogenesis Ubiquitin Binding Cell Projection Morphogenesis DNA-directed DNA Polymerase Activity Positive Regulation Of Mitophagy Regulation Of Developmental Growth Positive Regulation Of Autophagy Of Mitochondrion Macromolecule Metabolic Process Central Nervous System Development Positive Regulation Of Excitatory Postsynaptic Potential Reproductive Behavior Regulation Of Axonogenesis Regulation Of Peptidyl-serine Phosphorylation Dendritic Spine Organization Macromolecule Biosynthetic Process Amyloid-beta Complex Regulation Of Plasma Membrane Bounded Cell Projection Organization Growth Cone Lamellipodium Regulation Of Toll-like Receptor Signaling Pathway Regulation Of Cell Projection Organization Enzyme Binding Regulation Of Response To Calcium Ion Regulation Of Locomotion Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Cell Growth PCNA Complex Replisome Response To Dexamethasone 3-phosphoinositide-dependent Protein Kinase Activity Negative Regulation Of Synaptic Vesicle Clustering	Establishment Of Protein-containing Complex Localization To Telomere ATR-ATRIP Complex Establishment Of RNA Localization To Telomere Positive Regulation Of Telomerase Catalytic Core Complex Assembly Histone H2AXS139 Kinase Activity Positive Regulation Of Cellular Component Biogenesis Regulation Of Mitotic Cell Cycle MutSalpha Complex Binding DNA Repair MutLalpha Complex Binding Error-free Translesion Synthesis Smooth Muscle Cell Proliferation Vascular Associated Smooth Muscle Cell Proliferation Protein Localization To Chromosome, Telomeric Region Membrane Disassembly Regulation Of Cellular Response To Heat DNA Metabolic Process Nuclear Membrane Disassembly Regulation Of Cell Cycle Process Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator DNA Strand Resection Involved In Replication Fork Processing Replicative Senescence Positive Regulation Of Mitotic Cytokinesis Regulation Of Mitotic Cytokinesis DNA Damage Response Negative Regulation Of DNA Replication Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Nuclear Envelope Organization Protein Localization To Site Of Double-strand Break Translesion Synthesis Cellular Response To Gamma Radiation Response To Arsenic-containing Substance Positive Regulation Of Focal Adhesion Assembly Replication Fork Processing Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Cellular Component Organization Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Site Of DNA Damage Positive Regulation Of DNA Biosynthetic Process Interstrand Cross-link Repair Regulation Of Cell Cycle Positive Regulation Of Signal Transduction By P53 Class Mediator Muscle Cell Proliferation DNA Synthesis Involved In DNA Repair Postreplication Repair Positive Regulation Of Cytokinesis Negative Regulation Of Macroautophagy Mitotic Spindle Assembly Mitochondrial Nucleoid
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