RNF167 and SLC67A1

Number of citations of the paper that reports this interaction (PubMedID 16314844)
37

Data Source:
BioGRID (enzymatic study)

		RNF167	SLC67A1
Description		ring finger protein 167	solute carrier family 67 member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Lysosomal Membrane Endosome Cytosol Plasma Membrane Endosome Membrane Endomembrane System Membrane Organelle Membrane Endolysosome Membrane	Nuclear Envelope Cytoplasm Plasma Membrane Membrane Apical Plasma Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Transmembrane Transporter Activity Ubiquitin Protein Ligase Binding Xenobiotic Transmembrane Transporter Activity
	Biological Process	Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Cellular Response To Nutrient Levels Lysosome Localization Cellular Response To Amino Acid Starvation Protein K29-linked Ubiquitination Negative Regulation Of Cell Cycle Organelle Localization Regulation Of Synaptic Transmission, Glutamatergic Protein K63-linked Ubiquitination Protein K6-linked Ubiquitination Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of TORC1 Signaling Positive Regulation Of TORC1 Signaling Cellular Response To Leucine Starvation	Organic Cation Transport Xenobiotic Transport Transmembrane Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane
Pathways			SLC-mediated transport of organic cations Defective SLC22A18 causes lung cancer (LNCR) and embryonal rhabdomyosarcoma 1 (RMSE1)
Drugs
Diseases
GWAS		Keratoconus ( 33649486) Platelet count ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		34 interacting genes: ACTA1 AFG3L2 ATP2A1 CAPN3 CDC34 EGFR GRIA2 MDK MYH7 PDCD1 PTN RAB7A SESN2 SLC67A1 SUMO1 TAFA2 TAFA5 TMEM97 TOLLIP TTN UBE2A UBE2B UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2G2 UBE2K UBE2N UBE2T UBE2W	6 interacting genes: HSD17B11 NKX3-1 RNF167 RRM1 TLCD4 TMX2
Entrez ID		26001	5002
HPRD ID		15261	04024
Ensembl ID		ENSG00000108523	ENSG00000110628
Uniprot IDs		Q9H6Y7	A0A024RCG2 E9PRM7 Q96BI1
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein K48-linked Ubiquitination Protein Polyubiquitination Ubiquitin-protein Transferase Activity Protein Modification By Small Protein Conjugation ATP Binding Protein Ubiquitination Protein K11-linked Ubiquitination Nucleotide Binding Post-translational Protein Modification Proteolysis Involved In Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Macromolecule Catabolic Process Proteolysis Ubiquitin Protein Ligase Binding Protein Monoubiquitination Protein Catabolic Process Protein Modification Process Catabolic Process Transferase Activity Protein Metabolic Process Protein K63-linked Ubiquitination Ubiquitin-like Protein Transferase Activity Protein K6-linked Ubiquitination Proteasomal Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Modification Process Regulation Of Post-translational Protein Modification Negative Regulation Of TORC1 Signaling DNA Metabolic Process Protein Autoubiquitination Cellular Response To Interferon-beta Positive Regulation Of Protein Metabolic Process Cellular Response To Stress Negative Regulation Of TOR Signaling HULC Complex Response To Interferon-beta Regulation Of TORC1 Signaling Macromolecule Metabolic Process Postreplication Repair Skeletal Muscle Thin Filament Assembly DNA Repair Free Ubiquitin Chain Polymerization Positive Regulation Of Protein Modification Process Protein-containing Complex Regulation Of Protein Metabolic Process Leukocyte Chemotaxis Involved In Inflammatory Response DNA Damage Response Positive Regulation Of Post-translational Protein Modification	Positive Regulation Of Androgen Secretion MADS Box Domain Binding Ribonucleoside-diphosphate Reductase Activity Male Gonad Development Positive Regulation Of Mitotic Cell Cycle Gonad Development Dorsal Aorta Development Ribonucleoside-diphosphate Reductase Complex Ribonucleoside-diphosphate Reductase Activity, Thioredoxin Disulfide As Acceptor Steroid Dehydrogenase Activity Epithelial Cell Proliferation Involved In Salivary Gland Morphogenesis Salivary Gland Development Reproductive Structure Development Positive Regulation Of G0 To G1 Transition Purine Nucleotide Binding Androgen Catabolic Process Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
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