SYF2 and ARMC7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SYF2	ARMC7
Description		SYF2 pre-mRNA splicing factor	armadillo repeat containing 7
Image
GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Nuclear Speck U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Post-mRNA Release Spliceosomal Complex	Spliceosomal Complex
	Molecular Function	RNA Binding Protein Binding	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Processing Mitotic G2 DNA Damage Checkpoint Signaling Gastrulation Positive Regulation Of Cell Population Proliferation RNA Splicing Embryonic Organ Development	MRNA Processing RNA Splicing
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Glycated hemoglobin levels ( 28898252 34059833) Lead levels ( 26025379) Male-pattern baldness ( 27182965 29146897) Mean corpuscular volume ( 27863252) Plateletcrit ( 27863252) Urate levels in obese individuals ( 25811787)	Bipolar disorder ( 31043756)
Interacting Genes		5 interacting genes: APP ARMC7 CCNDBP1 MCM3 MLH1	71 interacting genes: ABI2 ABI3 AKAP19 APP CBY2 CCDC28B CCDC33 CDC42EP1 CFAP68 CHCHD3 CPSF6 CPSF7 DISC1 DPEP2NB DTX2 EFHC2 ESS2 GATA1 GIGYF1 HGS HOXA1 IKZF1 IKZF3 INCA1 KCTD13 KRT31 KRT34 KRT39 KRT40 KRT75 KRTAP13-1 KRTAP19-7 KRTAP6-3 LZTS2 MDFI NME4 PAK5 PIMREG PLEKHG4 PNMA6A REL RRP7A RUNDC3A SAXO1 SAXO5 SEPTIN14 SHISA6 SLAIN1 SPATC1L SPG21 SYF2 TASOR2 TCF4 TFIP11 TNFAIP1 TNNI1 TRIB3 TRIM27 TRIM42 TRIM54 USP54 VIM VPS37D YPEL3 ZBTB8A ZC2HC1C ZMAT5 ZNF140 ZNF426 ZNF669 ZNF764
Entrez ID		25949	79637
HPRD ID		07386	08649
Ensembl ID		ENSG00000117614	ENSG00000125449
Uniprot IDs		O95926	J3KST7 J3KTE5 Q9H6L4
PDB IDs		5MQF 5XJC 5YZG 6ICZ 6ID0 6ID1 6QDV 7A5P 7W59 7W5A 7W5B 8C6J 8I0U 8I0V 8I0W 8RO2 9FMD	7DVQ
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Cell Activation Involved In Immune Response Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Mitotic DNA Replication Initiation Single-stranded DNA Binding Alpha DNA Polymerase:primase Complex Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Guanine/thymine Mispair Binding Male Meiosis Chromosome Segregation Homologous Chromosome Segregation MutLalpha Complex Female Meiosis Chromosome Segregation Chiasma Late Recombination Nodule Mismatch Repair Complex Meiotic Metaphase I Homologous Chromosome Alignment Negative Regulation Of Mitotic Recombination Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Double-strand Break Repair Positive Regulation Of Isotype Switching To IgA Isotypes DNA Recombination	Intermediate Filament Supramolecular Fiber Organization Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Structural Constituent Of Skin Epidermis Protein Binding Cytoskeleton Organization Cytoskeleton Structural Molecule Activity MRNA Alternative Polyadenylation MRNA Cleavage Factor Complex
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