SYF2

Description		SYF2 pre-mRNA splicing factor
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GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Nuclear Speck U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Post-mRNA Release Spliceosomal Complex
	Molecular Function	RNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome In Utero Embryonic Development MRNA Processing Mitotic G2 DNA Damage Checkpoint Signaling Gastrulation Positive Regulation Of Cell Population Proliferation RNA Splicing Embryonic Organ Development
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Glycated hemoglobin levels ( 28898252 34059833) Lead levels ( 26025379) Male-pattern baldness ( 27182965 29146897) Mean corpuscular volume ( 27863252) Plateletcrit ( 27863252) Urate levels in obese individuals ( 25811787)
Novel Interacting Genes		5 novel interacting genes: APP ARMC7 CCNDBP1 MCM3 MLH1
Interacting Genes		5 interacting genes: APP ARMC7 CCNDBP1 MCM3 MLH1
Entrez ID		25949
HPRD ID		07386
Ensembl ID		ENSG00000117614
Uniprot IDs		O95926
PDB IDs		5MQF 5XJC 5YZG 6ICZ 6ID0 6ID1 6QDV 7A5P 7W59 7W5A 7W5B 8C6J 8I0U 8I0V 8I0W 8RO2 9FMD
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Cell Activation Involved In Immune Response Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Mitotic DNA Replication Initiation Single-stranded DNA Binding Alpha DNA Polymerase:primase Complex Meiotic Spindle Midzone Assembly Meiotic Metaphase Chromosome Alignment Guanine/thymine Mispair Binding Male Meiosis Chromosome Segregation Homologous Chromosome Segregation MutLalpha Complex Female Meiosis Chromosome Segregation Chiasma Late Recombination Nodule Mismatch Repair Complex Meiotic Metaphase I Homologous Chromosome Alignment Negative Regulation Of Mitotic Recombination Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Double-strand Break Repair Positive Regulation Of Isotype Switching To IgA Isotypes DNA Recombination
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