TXN2 and DCTD

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		TXN2	DCTD
Description		thioredoxin 2	dCMP deaminase
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GO Annotations	Cellular Component	Nucleolus Mitochondrion Mitochondrial Matrix	Cytoplasm Cytosol
	Molecular Function	Protein Binding Protein-disulfide Reductase Activity	Catalytic Activity DCMP Deaminase Activity Protein Binding Zinc Ion Binding Hydrolase Activity Identical Protein Binding Metal Ion Binding 5-hydroxymethyl-dUMP N-hydrolase Activity
	Biological Process	Cell Redox Homeostasis	Pyrimidine Nucleotide Metabolic Process DUMP Biosynthetic Process DTMP Biosynthetic Process Nucleotide Biosynthetic Process Nucleoside Salvage
Pathways		Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species	Interconversion of nucleotide di- and triphosphates
Drugs
Diseases
GWAS			Diisocyanate-induced asthma ( 25918132) Metabolite levels ( 23823483) Obesity-related traits ( 23251661) Wegener's granulomatosis ( 23740775)
Interacting Genes		79 interacting genes: ABI3 AGTRAP ALDOB ANKRD36B AP2B1 BCAS2 CCDC197 CDCA4 CEP70 CGGBP1 CHMP1A CIB4 CRACR2B CSTPP1 DCTD DDIT3 ETHE1 FAM9B FHL5 GOLGA6L9 GPRASP2 GPRASP3 GTPBP2 GUCD1 HAUS1 HAUS8 KAZN KRT18 KRT27 KRT40 LCN2 MAGEA11 MAGEA4 MAGEB2 MAPRE2 MAPRE3 MDFI MEOX2 MIPOL1 MLH1 MRFAP1 MRFAP1L1 MTUS2 MYL9 NUTM1 ODAD1 PEX19 POMC PPCDC PPP1R16B PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SAT1 SCYL3 SHARPIN SPTA1 SSNA1 STN1 STUB1 SUN2 SYCE1 TFIP11 THAP1 TIFA TMOD4 TRIM21 TRIP6 TTC32 UCHL5 UQCC2 VIM VPS52 ZBTB14 ZMYND12 ZSCAN32	15 interacting genes: CEP76 CTLA4 DYRK1A FGF12 FXR1 GORASP2 LNX1 MALSU1 NIF3L1 NUDT18 PICK1 PSMA1 SDCBP TXN2 UBE2I
Entrez ID		25828	1635
HPRD ID		07161	09623
Ensembl ID		ENSG00000100348	ENSG00000129187
Uniprot IDs		Q99757	P32321
PDB IDs		1UVZ 1W4V 1W89	2W4L
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Microtubule Organizing Center Organelle Organization Cytoskeleton Organization Cytoskeleton Membraneless Organelle Assembly Spindle Assembly Regulation Of Microtubule Cytoskeleton Organization Spindle Organization Synaptonemal Complex Microtubule Cytoskeleton Organization Cytoplasm Microtubule-based Process
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