TXN2 and MYL9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TXN2	MYL9
Description		thioredoxin 2	myosin light chain 9
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Mitochondrion Mitochondrial Matrix	Stress Fiber Cytoplasm Cytosol Cytoskeleton Muscle Myosin Complex Cell Cortex Myosin Complex Myosin II Complex Myofibril Z Disc
	Molecular Function	Protein Binding Protein-disulfide Reductase Activity	Structural Constituent Of Cytoskeleton Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Myosin Heavy Chain Binding Metal Ion Binding
	Biological Process	Cell Redox Homeostasis	Regulation Of Muscle Contraction Myofibril Assembly Stress Fiber Assembly Platelet Aggregation
Pathways		Degradation of cysteine and homocysteine Detoxification of Reactive Oxygen Species	EPHA-mediated growth cone collapse Sema4D induced cell migration and growth-cone collapse Smooth Muscle Contraction RHO GTPases activate PKNs RHO GTPases activate CIT RHO GTPases Activate ROCKs RHO GTPases activate PAKs RHO GTPases activate PAKs RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Diseases
GWAS
Interacting Genes		79 interacting genes: ABI3 AGTRAP ALDOB ANKRD36B AP2B1 BCAS2 CCDC197 CDCA4 CEP70 CGGBP1 CHMP1A CIB4 CRACR2B CSTPP1 DCTD DDIT3 ETHE1 FAM9B FHL5 GOLGA6L9 GPRASP2 GPRASP3 GTPBP2 GUCD1 HAUS1 HAUS8 KAZN KRT18 KRT27 KRT40 LCN2 MAGEA11 MAGEA4 MAGEB2 MAPRE2 MAPRE3 MDFI MEOX2 MIPOL1 MLH1 MRFAP1 MRFAP1L1 MTUS2 MYL9 NUTM1 ODAD1 PEX19 POMC PPCDC PPP1R16B PSME3 RABAC1 RABGEF1 RBM45 REEP6 RPIA SAT1 SCYL3 SHARPIN SPTA1 SSNA1 STN1 STUB1 SUN2 SYCE1 TFIP11 THAP1 TIFA TMOD4 TRIM21 TRIP6 TTC32 UCHL5 UQCC2 VIM VPS52 ZBTB14 ZMYND12 ZSCAN32	10 interacting genes: CDC42BPA CEP250 HSPB1 LRRK2 MSGN1 MYH9 PPP1R16B PRPF19 SLC12A5 TXN2
Entrez ID		25828	10398
HPRD ID		07161	17619
Ensembl ID		ENSG00000100348	ENSG00000101335
Uniprot IDs		Q99757	A0A384NY64 P24844
PDB IDs		1UVZ 1W4V 1W89
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Protein Binding Microtubule Organizing Center Organelle Organization Cytoskeleton Organization Cytoskeleton Membraneless Organelle Assembly Spindle Assembly Regulation Of Microtubule Cytoskeleton Organization Spindle Organization Synaptonemal Complex Microtubule Cytoskeleton Organization Cytoplasm Microtubule-based Process	Actomyosin Cytoskeleton Negative Regulation Of Protein Kinase C Signaling Platelet Aggregation Spindle Homotypic Cell-cell Adhesion Regulation Of Protein Processing Cell Leading Edge Cortical Granule Exocytosis Regulation Of Protein Maturation Cell Projection Thermosensory Behavior Cellular Response To Curcumin Caveola Neck GTP-dependent Protein Kinase Activity Wnt Signalosome Assembly Regulation Of Anatomical Structure Morphogenesis Uropod Organization Negative Regulation Of Actin Filament Severing Positive Regulation Of Protein Processing In Phagocytic Vesicle Regulation Of Cellular PH Regulation Of Intracellular PH Negative Regulation Of Late Endosome To Lysosome Transport Amphisome Peroxidase Inhibitor Activity Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion Beta-catenin Destruction Complex Binding Intracellular Protein Localization Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Positive Regulation Of Tumor Necrosis Factor Production Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Protein Kinase C Inhibitor Activity Identical Protein Binding Myosin II Filament Actomyosin Structure Organization Regulation Of Centriole-centriole Cohesion Regulation Of PH Positive Regulation Of Protein Autoubiquitination Response To Curcumin Actomyosin Contractile Ring Regulation Of Protein Kinase C Signaling Cortical Granule Cytoplasmic Actin-based Contraction Involved In Cell Motility Regulation Of Postsynapse Organization Cytoplasmic Side Of Mitochondrial Outer Membrane Positive Regulation Of Dopamine Receptor Signaling Pathway Multivesicular Body, Internal Vesicle Regulation Of CAMKK-AMPK Signaling Cascade Regulation Of Branching Morphogenesis Of A Nerve Regulation Of Synaptic Vesicle Transport
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