MMS22L and DNAJC3

		MMS22L	DNAJC3
Description		MMS22 like, DNA repair protein	DnaJ heat shock protein family (Hsp40) member C3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Chromosome Cytosol FACT Complex Site Of Double-strand Break MCM Complex Nuclear Replication Fork Site Of DNA Damage	Extracellular Region Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cytosol Membrane Azurophil Granule Lumen Extracellular Exosome Extracellular Vesicle
	Molecular Function	DNA Binding Single-stranded DNA Binding Protein Binding	Protein Kinase Inhibitor Activity Protein Kinase Binding Protein-folding Chaperone Binding Misfolded Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Repair Chromatin Organization DNA Damage Response Replication Fork Processing Protein Localization To Chromatin	Regulation Of Translation Response To Unfolded Protein Protein Folding In Endoplasmic Reticulum Response To Endoplasmic Reticulum Stress Positive Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Negative Regulation Of Apoptotic Process Proteolysis Involved In Protein Catabolic Process Defense Response To Virus Cellular Response To Cold Negative Regulation Of Translation In Response To Endoplasmic Reticulum Stress Negative Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation
Pathways			Viral mRNA Translation XBP1(S) activates chaperone genes Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Neutrophil degranulation Post-translational protein phosphorylation PKR-mediated signaling
Drugs
Diseases
GWAS		Adult body size ( 32376654) Anxiety ( 33859377) Automobile speeding propensity ( 30643258) Body mass index ( 25673413 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Chronotype ( 30696823) Gut microbiota (bacterial taxa) ( 27694959) Hand grip strength ( 29691431) Morning person ( 30696823) Multiple sclerosis (OCB status) ( 23785401) Number of sexual partners ( 30643258) Photic sneeze reflex ( 27182965) Post bronchodilator FEV1 in COPD ( 26634245) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)	Body mass index ( 28552196)
Interacting Genes		13 interacting genes: DERL2 DNAJC3 ESCO2 FBXW7 KRT37 NDUFAF4 PCDHB16 RAD51 RARS2 RPA1 TRRAP TTPA WASF1	9 interacting genes: DNAJB1 EIF2AK2 EIF2AK3 HSPA1A MMS22L OGT THAP12 TIRAP UBC
Entrez ID		253714	5611
HPRD ID		12865	03114
Ensembl ID		ENSG00000146263	ENSG00000102580
Uniprot IDs		E2QRD4 Q6ZRQ5	A8KA82 Q13217
PDB IDs			2Y4T 2Y4U
Enriched GO Terms of Interacting Partners?		Lateral Element Site Of Double-strand Break Chromosome Organization Telomere Maintenance Via Telomere Lengthening Nuclear Chromosome Positive Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Negative Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation Cellular Response To Stress Condensed Chromosome Response To Glucoside Double-strand Break Repair Condensed Nuclear Chromosome DNA Repair Male Germ Cell Nucleus Negative Regulation Of Establishment Of Blood-brain Barrier Sister Chromatid Cohesion Positive Regulation Of Translational Initiation In Response To Stress Response To Unfolded Protein Negative Regulation Of Translation In Response To Endoplasmic Reticulum Stress Mitotic Recombination-dependent Replication Fork Processing DNA Metabolic Process DNA Damage Response DNA Strand Exchange Activity Regulation Of Double-strand Break Repair Via Homologous Recombination Presynaptic Intermediate Filament Cytoskeleton Regulation Of Establishment Of Blood-brain Barrier Vitamin E Binding Dendritic Transport Of Mitochondrion Parkin-FBXW7-Cul1 Ubiquitin Ligase Complex Negative Regulation Of Hepatocyte Proliferation Phosphothreonine Residue Binding Arginyl-tRNA Aminoacylation Arginine-tRNA Ligase Activity Post-translational Protein Acetylation Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress Meiotic Cell Cycle DNA Strand Invasion Telomere Maintenance Single-stranded DNA Binding DNA Recombinase Assembly Cellular Response To Cisplatin Cellular Response To Camptothecin Response To Toxic Substance PML Body Single-stranded Telomeric DNA Binding Protein Localization To Chromosome Vitamin E Metabolic Process Positive Regulation Of Neurotrophin TRK Receptor Signaling Pathway Ubiquitin Recycling	Eukaryotic Translation Initiation Factor 2alpha Kinase Activity Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Inclusion Body Assembly Response To Unfolded Protein Regulation Of Translational Initiation Misfolded Protein Binding Regulation Of Protein-containing Complex Assembly Regulation Of Inclusion Body Assembly Response To Temperature Stimulus Positive Regulation Of Cytokine Production Regulation Of Cellular Response To Stress Negative Regulation Of Translation Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Gene Expression Response To Stress Negative Regulation Of Protein Metabolic Process Post-transcriptional Regulation Of Gene Expression Response To Endoplasmic Reticulum Stress Transcription Regulator Inhibitor Activity Cellular Response To Nutrient Levels Negative Regulation Of Translational Initiation Cellular Response To Heat Positive Regulation Of Pattern Recognition Receptor Signaling Pathway Protein Folding Chaperone Positive Regulation Of Interleukin-8 Production Regulation Of Cytokine Production Cellular Response To Amino Acid Starvation Response To Amino Acid Starvation Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Interleukin-15 Production Cellular Response To Stress Negative Regulation Of Macromolecule Metabolic Process Cytosol Positive Regulation Of Chemokine Production Negative Regulation Of Protein Ubiquitination Positive Regulation Of NF-kappaB Transcription Factor Activity Translational Initiation Positive Regulation Of Multicellular Organismal Process Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway Response To Heat Regulation Of Interleukin-8 Production Negative Regulation Of Metabolic Process Negative Regulation Of Post-translational Protein Modification Regulation Of Response To Endoplasmic Reticulum Stress Denatured Protein Binding Regulation Of Translation Regulation Of Chemokine Production Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?