PLA2G15 and COG4

		PLA2G15	COG4
Description		phospholipase A2 group XV	component of oligomeric golgi complex 4
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleoplasm Lysosome Membrane Extracellular Exosome	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Membrane Golgi Transport Complex Trans-Golgi Network Membrane
	Molecular Function	Phosphatidylcholine Lysophospholipase Activity Phospholipase A2 Activity Protein Binding Phospholipid Binding Zinc Ion Binding O-acyltransferase Activity Phospholipase A1 Activity Acylglycerol O-acyltransferase Activity Transferase Activity Acyltransferase Activity Hydrolase Activity Metal Ion Binding Calcium-independent Phospholipase A2 Activity	Protein Binding Identical Protein Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Phospholipid Metabolic Process Glycerophospholipid Metabolic Process Diacylglycerol Biosynthetic Process Phosphatidylserine Metabolic Process Ceramide Metabolic Process Fatty Acid Catabolic Process Lipid Catabolic Process Phosphatidylcholine Catabolic Process Phosphatidylethanolamine Catabolic Process Phosphatidylcholine Metabolic Process Phosphatidylglycerol Metabolic Process	Retrograde Transport, Vesicle Recycling Within Golgi Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Protein Transport Glycosylation
Pathways		Hydrolysis of LPC	COPI-mediated anterograde transport Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Eosinophil count ( 27863252) Eosinophil percentage of white cells ( 27863252) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Serum metabolite levels ( 33031748) Waist circumference adjusted for body mass index ( 34021172)	Brain morphology (MOSTest) ( 32665545) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Liver enzyme levels (alkaline phosphatase) ( 33972514) Malaria ( 31844061) Menarche (age at onset) ( 25231870) Weight ( 28552196)
Interacting Genes		11 interacting genes: COG4 DDX19B EDC4 FBXL9P IMMT PLEKHG4 RNF7 SF3B3 TMEM208 VPS4A WWP2	21 interacting genes: ANKRD11 APC BEX2 COG1 COG2 COG5 COG7 CTNNA3 DSCAM FAM110A FARSA ITSN1 MTNR1B NRIP1 PLA2G15 PSMA1 RSPH1 SEPTIN2 SORBS3 TTC3 TXNDC9
Entrez ID		23659	25839
HPRD ID		07128	08444
Ensembl ID		ENSG00000103066	ENSG00000103051
Uniprot IDs		B4DJW4 Q8NCC3	A0A0A0MS45 A0A6I8PIQ6 J3KNI1 Q8N8L9 Q9H9E3
PDB IDs		4X90 4X91 4X92 4X93 4X94 4X95 4X97 6MTW	3HR0
Enriched GO Terms of Interacting Partners?			Golgi Transport Complex Retrograde Transport, Vesicle Recycling Within Golgi Intra-Golgi Vesicle-mediated Transport Trans-Golgi Network Membrane Golgi Organization Glycosylation Golgi Vesicle Transport
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