PLA2G15 and DDX19B

		PLA2G15	DDX19B
Description		phospholipase A2 group XV	DEAD-box helicase 19B
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleoplasm Lysosome Membrane Extracellular Exosome	Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Cytoplasm Cytoplasmic Stress Granule Membrane Extracellular Exosome
	Molecular Function	Phosphatidylcholine Lysophospholipase Activity Phospholipase A2 Activity Protein Binding Phospholipid Binding Zinc Ion Binding O-acyltransferase Activity Phospholipase A1 Activity Acylglycerol O-acyltransferase Activity Transferase Activity Acyltransferase Activity Hydrolase Activity Metal Ion Binding Calcium-independent Phospholipase A2 Activity	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity MRNA Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Phospholipid Metabolic Process Glycerophospholipid Metabolic Process Diacylglycerol Biosynthetic Process Phosphatidylserine Metabolic Process Ceramide Metabolic Process Fatty Acid Catabolic Process Lipid Catabolic Process Phosphatidylcholine Catabolic Process Phosphatidylethanolamine Catabolic Process Phosphatidylcholine Metabolic Process Phosphatidylglycerol Metabolic Process	MRNA Export From Nucleus Poly(A)+ MRNA Export From Nucleus
Pathways		Hydrolysis of LPC
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Eosinophil count ( 27863252) Eosinophil percentage of white cells ( 27863252) Refractive error ( 32231278) Schizophrenia ( 25056061 29483656) Serum metabolite levels ( 33031748) Waist circumference adjusted for body mass index ( 34021172)	Apolipoprotein B levels ( 32203549) Brain morphology (MOSTest) ( 32665545) Malaria ( 31844061) Pursuit maintenance gain ( 29064472) Systolic blood pressure ( 30578418)
Interacting Genes		11 interacting genes: COG4 DDX19B EDC4 FBXL9P IMMT PLEKHG4 RNF7 SF3B3 TMEM208 VPS4A WWP2	18 interacting genes: APP B3GALT4 CEBPA DCK DYNC1I1 EIF4G3 FOXP1 IKBKG NUP214 PLA2G15 POT1 PRPSAP1 RACK1 RWDD2B SKP1 TERF1 UBC XPO7
Entrez ID		23659	11269
HPRD ID		07128	05781
Ensembl ID		ENSG00000103066	ENSG00000157349
Uniprot IDs		B4DJW4 Q8NCC3	A0A0U4B4U6 H3BQK0 Q9UMR2
PDB IDs		4X90 4X91 4X92 4X93 4X94 4X95 4X97 6MTW	3EWS 3FHC 3FHT 3FMO 3FMP 3G0H 6B4I 6B4J 6B4K
Enriched GO Terms of Interacting Partners?			Shelterin Complex Positive Regulation Of Proteolysis Protein Homodimerization Activity Nuclear Telomere Cap Complex Telomeric Loop Disassembly Telomere Capping Telomeric D-loop Disassembly G-rich Strand Telomeric DNA Binding Nuclear Export Signal Receptor Activity Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase Molecular Function Activator Activity RNA-templated DNA Biosynthetic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Telomere Maintenance Via Telomere Lengthening Telomeric DNA Binding Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Antigen Receptor-mediated Signaling Pathway Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Proteolysis Positive Regulation Of Toll Signaling Pathway Nucleoplasm Regulation Of Ubiquitin-dependent Protein Catabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Telomere Maintenance Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Cytoplasmic Side Of Nuclear Pore Protein Export From Nucleus Ganglioside Galactosyltransferase Activity Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Positive Regulation Of Protein Metabolic Process Negative Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Protein Catabolic Process Identical Protein Binding Regulation Of Telomere Maintenance Via Telomere Lengthening Acetylcholine Receptor Activator Activity
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