POLA2 and SNU13

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		POLA2	SNU13
Description		DNA polymerase alpha 2, accessory subunit	small nuclear ribonucleoprotein 13
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Alpha DNA Polymerase:primase Complex Cytosol Ciliary Basal Body	Dense Fibrillar Component Nucleus Nucleoplasm Spliceosomal Complex U4atac SnRNP Nucleolus Box C/D Methylation Guide SnoRNP Complex Small-subunit Processome Protein-containing Complex U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome Precatalytic Spliceosome Ribonucleoprotein Complex
	Molecular Function	DNA Binding Protein Binding	RNA Binding Protein Binding SnoRNA Binding U4 SnRNA Binding U4atac SnRNA Binding U3 SnoRNA Binding Box C/D Sno(s)RNA Binding ATPase Binding
	Biological Process	DNA Replication DNA Replication, Synthesis Of Primer DNA Replication Initiation Protein Import Into Nucleus	MRNA Splicing, Via Spliceosome Box C/D SnoRNP Assembly MRNA Processing Single Fertilization RNA Splicing Maturation Of SSU-rRNA Ribosome Biogenesis Ribosomal Small Subunit Biogenesis
Pathways		Inhibition of replication initiation of damaged DNA by RB1/E2F1 Polymerase switching on the C-strand of the telomere Telomere C-strand synthesis initiation DNA replication initiation Activation of the pre-replicative complex Polymerase switching Removal of the Flap Intermediate Processive synthesis on the lagging strand Defective pyroptosis	rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol mRNA Splicing - Major Pathway
Drugs		Dacarbazine	(S)-3-phenyllactic acid Anisomycin
Diseases
GWAS		Acne (severe) ( 24927181) Appendicular lean mass ( 33097823) Hip circumference adjusted for BMI ( 34021172) Serum uric acid levels ( 32514006)	Appendicular lean mass ( 33097823)
Interacting Genes		41 interacting genes: AGO2 AKTIP APP ARL2 ASCC2 ATL3 ATP5F1C CATSPERZ CPE CRELD1 DCP2 DDX24 DHX34 EIF6 EZH2 FAM219A FGFR3 FRZB HDAC6 HELB HGH1 IGFBP3 KCNE3 KDM2A KLF6 LRPAP1 MFHAS1 NR4A1 PARP1 POLA1 PRIM2 PRPF38A RBM23 SAC3D1 SETDB1 SNU13 STK40 TMEM216 ULK2 XPNPEP1 ZNRD2	16 interacting genes: CDKN2C CHST1 GTF3C1 HSPB2 LRIF1 MAP1LC3B NUFIP1 POLA2 PPIH RAD17 RBM10 RHOU SMN1 SMN2 SNW1 XRCC6
Entrez ID		23649	4809
HPRD ID		10160	03197
Ensembl ID		ENSG00000014138	ENSG00000100138
Uniprot IDs		A0A9L9PY44 H0YDR7 Q14181	P55769 Q6FHM6
PDB IDs		2KEB 4E2I 4Y97 5EXR 7OPL 7U5C 8B9D 8D0B 8D0K 8D9D 8QJ7 8VY3 9C8V	1E7K 2JNB 2OZB 3JCR 3SIU 3SIV 5O9Z 6AH0 6AHD 6QW6 6QX9 7MQ8 7MQ9 7MQA 8H6E 8H6J 8H6K 8H6L 8Q7N 8QO9 8QOZ 8QPA 8QPB 8QPE 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5 8Y6O
Enriched GO Terms of Interacting Partners?		DNA Replication, Synthesis Of Primer Regulation Of Phosphorus Metabolic Process Nucleic Acid Metabolic Process Collateral Sprouting RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Macromolecule Metabolic Process Alpha DNA Polymerase:primase Complex Regulation Of Glycolytic Process	RNA Splicing, Via Transesterification Reactions Nucleic Acid Metabolic Process RNA Splicing SMN Complex MRNA Processing Gemini Of Cajal Bodies RNA Processing Nucleobase-containing Compound Metabolic Process Nucleoplasm RNA Metabolic Process SMN-Sm Protein Complex DNA-templated Transcription Termination Nuclear Retinoic Acid Receptor Binding MRNA Metabolic Process Nuclear Matrix Nucleus Chromosome, Telomeric Region Rad17 RFC-like Complex Spliceosomal Complex Assembly Protein-RNA Complex Assembly Spliceosomal SnRNP Assembly Vascular Associated Smooth Muscle Cell Apoptotic Process Negative Regulation Of Ribosomal Large Subunit Export From Nucleus MRNA Splicing, Via Spliceosome Nucleolus Cajal Body RNA Binding Keratan Sulfotransferase Activity DNA End Binding Ku70:Ku80 Complex Cytoplasmic Ribonucleoprotein Granule Smooth Muscle Cell Apoptotic Process U4/U6 SnRNP
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