CBX7 and B3GNT5

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		CBX7	B3GNT5
Description		chromobox 7	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytosol PcG Protein Complex PRC1 Complex	Golgi Membrane Golgi Apparatus Membrane
	Molecular Function	Protein Binding	Protein Binding N-acetyl-beta-D-glucosaminide Beta-(1,3)-galactosyltransferase Activity Transferase Activity Glycosyltransferase Activity Hexosyltransferase Activity Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Organization	Protein Glycosylation Protein O-linked Glycosylation Lipid Metabolic Process Glycosphingolipid Biosynthetic Process Central Nervous System Development Glycolipid Biosynthetic Process Protein O-linked Glycosylation Via N-acetyl-galactosamine Sphingolipid Biosynthetic Process Carbohydrate Derivative Biosynthetic Process
Pathways			O-linked glycosylation of mucins Glycosphingolipid biosynthesis
Drugs
Diseases
GWAS		Hematocrit ( 32888494) Hemoglobin ( 32888494) Immunoglobulin light chain (AL) amyloidosis ( 28025584) Lymphocyte count ( 27863252 32888494) Menarche (age at onset) ( 25231870) Multiple myeloma ( 23955597 26007630 33875642) Multiple myeloma and monoclonal gammopathy ( 26007630) Neutrophil count ( 32888494) White blood cell count ( 27863252 32888494)
Interacting Genes		12 interacting genes: B3GNT5 H3-3A H3-4 H3C1 H3C14 PCGF1 PCGF5 PCGF6 RING1 RNF2 SUV39H2 ZRANB1	2 interacting genes: CBX7 DCDC2
Entrez ID		23492	84002
HPRD ID		12234	12511
Ensembl ID		ENSG00000100307	ENSG00000176597
Uniprot IDs		B0QYP2 O95931 Q4PNR6	Q9BYG0
PDB IDs		2K1B 2L12 2L1B 3GS2 4MN3 5EPJ 6V2R 8SII
Enriched GO Terms of Interacting Partners?		Chromatin Remodeling PRC1 Complex Chromatin Organization PcG Protein Complex Structural Constituent Of Chromatin Nucleoplasm Nucleosome Assembly Epigenetic Regulation Of Gene Expression Nucleosome Nucleosome Organization Histone H2AK119 Ubiquitin Ligase Activity Chromosome Protein-DNA Complex Assembly Sex Chromatin Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Protein Heterodimerization Activity Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Zinc Ion Binding Negative Regulation Of Metabolic Process Nucleus Negative Regulation Of RNA Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Heterochromatin Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase Activity Regulation Of Gene Expression Gene Expression Regulation Of Macromolecule Biosynthetic Process RING-like Zinc Finger Domain Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Chromosome Condensation Regulation Of Macromolecule Metabolic Process Ubiquitin Ligase Complex Spermatogonial Cell Division Protein K29-linked Deubiquitination Histone H3K9 Trimethyltransferase Activity X Chromosome Pericentric Heterochromatin Formation Telomere Organization Protein K33-linked Deubiquitination Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Chromatin Binding Regulation Of Centromere Complex Assembly Heterochromatin Formation
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