PHF24 and THBD

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PHF24	THBD
Description		PHD finger protein 24	thrombomodulin
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GO Annotations	Cellular Component	Nucleus Cytoplasm Synaptic Vesicle Membrane Glutamatergic Synapse	Extracellular Space Vacuolar Membrane Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Apicolateral Plasma Membrane Serine-type Endopeptidase Complex
	Molecular Function	Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Transmembrane Signaling Receptor Activity Calcium Ion Binding Protein Binding Signaling Receptor Activity
	Biological Process	Gamma-aminobutyric Acid Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Synaptic Transmission, GABAergic Negative Regulation Of DNA-templated Transcription Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain	Proteolysis Female Pregnancy Blood Coagulation Hemostasis Response To X-ray Negative Regulation Of Platelet Activation Negative Regulation Of Blood Coagulation Zymogen Activation Response To Lipopolysaccharide Negative Regulation Of Coagulation Response To CAMP Negative Regulation Of Fibrinolysis Blood Coagulation, Common Pathway
Pathways			Common Pathway of Fibrin Clot Formation Cell surface interactions at the vascular wall
Drugs			Drotrecogin alfa Ibuprofen Dexibuprofen
Diseases			Inherited thrombophilia
GWAS			Blood protein levels in cardiovascular risk ( 28369058) Lung function (FVC) in asthma ( 32989782) PR interval in Tripanosoma cruzi seropositivity ( 24324551) Venous thromboembolism ( 26888256)
Interacting Genes		6 interacting genes: GNAI3 PFDN5 SIGMAR1 THBD TRIM35 ZNF552	33 interacting genes: AIG1 APOC2 APOC4 AQP6 CD79A CIDEB CYBC1 EBP ERGIC3 F2 FAM209A FCER1G GPR152 GPX8 KIR2DL3 LMNA MMGT1 MTIF3 MUC1 PDZK1IP1 PF4 PHF24 PROC PSENEN RHBDD2 SERPINA5 SLC10A6 SLC19A3 SLC35H1 TMEM14B TMEM35A TMEM86B TMX2
Entrez ID		23349	7056
HPRD ID		19412	01764
Ensembl ID		ENSG00000122733	ENSG00000178726
Uniprot IDs		Q9UPV7	P07204
PDB IDs		1WIL 5XHT	1ADX 1DQB 1DX5 1EGT 1FGD 1FGE 1HLT 1TMR 1ZAQ 2ADX 3GIS 5TO3 7T4R
Enriched GO Terms of Interacting Partners?		RNA Polymerase III Assembly RNA Polymerase I Assembly RNA Polymerase II Core Complex Assembly Blood Coagulation, Common Pathway	Membrane Endoplasmic Reticulum Membrane Negative Regulation Of Coagulation Negative Regulation Of Blood Coagulation Negative Regulation Of Hemostasis Lipid Transport Protein Binding Organic Hydroxy Compound Transport Identical Protein Binding Negative Regulation Of Wound Healing Regulation Of Hemostasis Regulation Of Blood Coagulation Endoplasmic Reticulum Positive Regulation Of Protein Localization To Cell Surface Very-low-density Lipoprotein Particle
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