PHF24 and SIGMAR1

		PHF24	SIGMAR1
Description		PHD finger protein 24	sigma non-opioid intracellular receptor 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Synaptic Vesicle Membrane Glutamatergic Synapse	Nucleus Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Cytosol Plasma Membrane Postsynaptic Density Membrane Growth Cone Cytoplasmic Vesicle Cell Projection Synapse Postsynaptic Membrane Anchoring Junction Postsynapse Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	G Protein-coupled Opioid Receptor Activity Protein Binding Signaling Receptor Activity Identical Protein Binding
	Biological Process	Gamma-aminobutyric Acid Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Synaptic Transmission, GABAergic Negative Regulation Of DNA-templated Transcription Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain	Lipid Transport Nervous System Development G Protein-coupled Opioid Receptor Signaling Pathway Regulation Of Neuron Apoptotic Process Protein Homotrimerization Regulation Of Postsynapse Assembly
Pathways			Potential therapeutics for SARS
Drugs			Amitriptyline Remoxipride Haloperidol Dextromethorphan Nortriptyline Fenfluramine Pentazocine Naltrexone Cocaine Hydrocodone Sertraline Dimethyltryptamine Prasterone Phencyclidine Pimavanserin Noscapine Captodiame Pentoxyverine
Diseases
GWAS
Interacting Genes		6 interacting genes: GNAI3 PFDN5 SIGMAR1 THBD TRIM35 ZNF552	15 interacting genes: ANK2 DCAF12 DNAJB5 GHSR GNE ITPR3 NFX1 PDZD11 PHF24 RECK RUSC2 SPAG8 SPINK4 SRI VCP
Entrez ID		23349	10280
HPRD ID		19412	03580
Ensembl ID		ENSG00000122733	ENSG00000147955
Uniprot IDs		Q9UPV7	A0A7P0T9D5 A0A7P0Z4C2 B4DR71 Q99720
PDB IDs		1WIL 5XHT	5HK1 5HK2 6DJZ 6DK0 6DK1
Enriched GO Terms of Interacting Partners?		RNA Polymerase III Assembly RNA Polymerase I Assembly RNA Polymerase II Core Complex Assembly Blood Coagulation, Common Pathway
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