FRMD4B and CYTH3

Number of citations of the paper that reports this interaction (PubMedID 11445584)
0

Data Source:
HPRD (in vivo)

		FRMD4B	CYTH3
Description		FERM domain containing 4B	cytohesin 3
Image		No pdb structure
GO Annotations	Cellular Component	Ruffle Extracellular Space Cytoplasm Cytoskeleton Adherens Junction Bicellular Tight Junction Anchoring Junction	Golgi Membrane Ruffle Nucleoplasm Cytoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Membrane Anchoring Junction
	Molecular Function		Guanyl-nucleotide Exchange Factor Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Lipid Binding
	Biological Process	Establishment Of Epithelial Cell Polarity	Regulation Of ARF Protein Signal Transduction Positive Regulation Of Cell Adhesion Golgi Vesicle Transport Establishment Of Epithelial Cell Polarity
Pathways			Intra-Golgi traffic
Drugs			Inositol 1,3,4,5-Tetrakisphosphate Inositol-(1,3,4,5,6)-Pentakisphosphate
Diseases
GWAS		Atrial fibrillation ( 30061737) Carotid intima media thickness x smoking interaction ( 32117412) Celiac disease ( 20190752 31591516) dexamethasone sensitivity in B-cell precursor acute lymphoblastic leukaemia ( 33002292) Fast beta electroencephalogram ( 28040410) Hepcidin/ferritin ratio ( 27846281) High myopia ( 32428537) PR interval ( 30046033 32439900) prednisolone sensitivity in B-cell precursor acute lymphoblastic leukaemia ( 33002292) Renal underexcretion gout ( 32238385) Resting heart rate ( 27798624) Resting-state electroencephalogram vigilance ( 29703947) Sphingomyelin 24:0 levels ( 31560688) Trunk fat mass ( 28552196)	Asthma ( 27611488) Body mass index ( 26426971) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321) Shigella-associated diarrhea ( 33649051)
Interacting Genes		2 interacting genes: CYTH3 RSPH1	10 interacting genes: ARFIP2 CALCOCO1 CNKSR1 CYTIP FRMD4B IFI35 ITSN1 PIK3CA SNCA TAMALIN
Entrez ID		23150	9265
HPRD ID		19415	05469
Ensembl ID		ENSG00000114541	ENSG00000008256
Uniprot IDs		B3KNA2 Q6PEW6 Q9Y2L6	B7Z2V9 O43739
PDB IDs			4KAX 6U3E 6U3G
Enriched GO Terms of Interacting Partners?		Radial Spoke Head 1 Radial Spoke Head 3 Radial Spoke Head Outer Dense Fiber Radial Spoke Meiotic Spindle Regulation Of ARF Protein Signal Transduction Establishment Of Epithelial Cell Polarity 9+2 Motile Cilium Phosphatidylinositol-3,4,5-trisphosphate Binding Condensed Nuclear Chromosome Axoneme Assembly	Cell Cortex Cytoplasm Macrophage Activation Regulation Of Cellular Respiration Presynaptic Endocytosis Synaptic Vesicle Endocytosis Regulation Of Endocytosis Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission
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