CYTH3

Description		cytohesin 3
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GO Annotations	Cellular Component	Golgi Membrane Ruffle Nucleoplasm Cytoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Membrane Anchoring Junction
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Lipid Binding
	Biological Process	Regulation Of ARF Protein Signal Transduction Positive Regulation Of Cell Adhesion Golgi Vesicle Transport Establishment Of Epithelial Cell Polarity
Pathways		Intra-Golgi traffic
Drugs		Inositol 1,3,4,5-Tetrakisphosphate Inositol-(1,3,4,5,6)-Pentakisphosphate
Diseases
GWAS		Asthma ( 27611488) Body mass index ( 26426971) Cerebrospinal fluid p-tau levels in mild cognitive impairment ( 29274321) Shigella-associated diarrhea ( 33649051)
Novel Interacting Genes		10 novel interacting genes: ARFIP2 CALCOCO1 CNKSR1 CYTIP FRMD4B IFI35 ITSN1 PIK3CA SNCA TAMALIN
Interacting Genes		10 interacting genes: ARFIP2 CALCOCO1 CNKSR1 CYTIP FRMD4B IFI35 ITSN1 PIK3CA SNCA TAMALIN
Entrez ID		9265
HPRD ID		05469
Ensembl ID		ENSG00000008256
Uniprot IDs		B7Z2V9 O43739
PDB IDs		4KAX 6U3E 6U3G
Enriched GO Terms of Interacting Partners?		Cell Cortex Cytoplasm Macrophage Activation Regulation Of Cellular Respiration Presynaptic Endocytosis Synaptic Vesicle Endocytosis Regulation Of Endocytosis Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission
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