FNBP1 and RND2

Number of citations of the paper that reports this interaction (PubMedID 12244061)
0

Data Source:
HPRD (two hybrid, in vitro)

		FNBP1	RND2
Description		formin binding protein 1	Rho family GTPase 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Cytosol Cytoskeleton Plasma Membrane Clathrin-coated Pit Cell Cortex Membrane Cytoplasmic Vesicle	Acrosomal Membrane Cytosol Plasma Membrane Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding Lipid Binding Identical Protein Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Protein Kinase Binding
	Biological Process	Endocytosis Signal Transduction	Actin Filament Organization Signal Transduction Small GTPase-mediated Signal Transduction Regulation Of Actin Cytoskeleton Organization Collateral Sprouting Positive Regulation Of Collateral Sprouting
Pathways		Clathrin-mediated endocytosis CDC42 GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RND2 GTPase cycle	RND2 GTPase cycle
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Femur bone mineral density x serum urate levels interaction ( 34046847) Gut microbiota relative abundance (unassigned genus belonging to family Clostridiales) ( 33208821) LDL peak particle diameter (total fat intake interaction) ( 26112879) Pediatric autoimmune diseases ( 26301688) Physiological dysregulation (Mahalanobis distance) ( 32235003)	Coronary artery disease ( 29212778)
Interacting Genes		14 interacting genes: AGTR1 AKAP9 ARHGAP17 CBL CDC42 CEBPA DNM1 FASLG ITSN1 PDE6G RND2 SNX2 TNKS WASL	6 interacting genes: FNBP1 MEOX2 RACGAP1 TUBG1 UBXN11 VPS4A
Entrez ID		23048	8153
HPRD ID		10446	03332
Ensembl ID		ENSG00000187239	ENSG00000108830
Uniprot IDs		A0A8V8TQ35 A0A994J3U5 A0A994J3V8 B7ZL13 B7ZL14 H0Y7W6 Q96RU3	P52198
PDB IDs		2EFL
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Component Organization Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Cellular Component Organization Positive Regulation Of ERBB Signaling Pathway Positive Regulation Of Endocytosis Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Cytoplasmic Vesicle Regulation Of Plasma Membrane Organization Regulation Of Endocytosis Dendritic Spine Morphogenesis Regulation Of Postsynapse Organization Positive Regulation Of Filopodium Assembly Signal Transduction Positive Regulation Of Transport Endocytosis Dendritic Spine Organization Vesicle Budding From Membrane Protein Kinase Binding Lamellipodium Plasma Membrane Macrophage Differentiation Neuron Projection Organization Regulation Of Filopodium Assembly Postsynapse Organization Angiotensin Type I Receptor Activity Regulation Of Vesicle-mediated Transport Regulation Of Cytoskeleton Organization RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Clathrin Coat Assembly Involved In Endocytosis Positive Regulation Of Receptor-mediated Endocytosis Glutamatergic Synapse Regulation Of Transport Small GTPase-mediated Signal Transduction Bradykinin Receptor Binding Membrane Organization Positive Regulation Of Phosphatidylserine Exposure On Apoptotic Cell Surface Cellular Response To Type II Interferon Import Into Cell Establishment Of Organelle Localization Cell Projection Morphogenesis Actin Filament Organization GBD Domain Binding Storage Vacuole Response To Vitamin B2 C/EBP Complex Vesicle Scission Clathrin-coated Pit Clathrin-dependent Synaptic Vesicle Endocytosis Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Telomeric	Spindle Cytoskeleton Flemming Body Cytokinetic Process Microtubule Nucleator Activity Actomyosin Contractile Ring Contraction Late Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Late Endosomal Microautophagy Cytoskeleton-dependent Cytokinesis Regulation Of Cytokinesis Contractile Ring Contraction Positive Regulation Of Viral Budding Via Host ESCRT Complex Centralspindlin Complex Somite Specification Polar Microtubule Mitotic Cytokinesis Checkpoint Signaling Regulation Of Cell Division Midbody Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Actomyosin Contractile Ring Assembly ATP-dependent Protein Disaggregase Activity Vesicle Uncoating Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Cytokinesis Mitotic Nuclear Membrane Reassembly ESCRT III Complex Disassembly ESCRT Complex Disassembly Mitotic Spindle Midzone Assembly Gamma-tubulin Ring Complex Gamma-tubulin Complex ATPase Complex Sulfate Transmembrane Transport Spindle Midzone Assembly Cytoplasm Segment Specification Somite Development Microtubule Mitotic Spindle Microtubule Lipid Binding Endosomal Vesicle Fusion Viral Budding From Plasma Membrane Negative Regulation Of Cell Division Vacuolar Membrane Positive Regulation Of Exosomal Secretion Late Endosome To Lysosome Transport Regulation Of Exosomal Secretion Meiotic Spindle Organization Pericentriolar Material Intracellular Cholesterol Transport Viral Budding Via Host ESCRT Complex
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