SCMH1 and LYPLA2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SCMH1	LYPLA2
Description		Scm polycomb group protein homolog 1	lysophospholipase 2
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleoplasm Cytoplasm Golgi Stack Cytosol Extracellular Exosome
	Molecular Function	Chromatin Binding Protein Binding Histone Binding	Phosphatidylcholine Lysophospholipase Activity Protein Binding Palmitoyl-(protein) Hydrolase Activity Hydrolase Activity Cadherin Binding
	Biological Process	Regulation Of DNA-templated Transcription Heterochromatin Formation Negative Regulation Of DNA-templated Transcription	Lipid Metabolic Process Fatty Acid Metabolic Process Axon Guidance Acylglycerol Catabolic Process Macromolecule Depalmitoylation Prostaglandin Catabolic Process
Pathways			L1CAM interactions
Drugs		Mercaptoethanol
Diseases
GWAS		Adventurousness ( 30643258) Appendicular lean mass ( 33097823) Atrial fibrillation ( 29892015 30061737) General risk tolerance (MTAG) ( 30643258) Height ( 18391952 20881960 23563607 25282103) Hip circumference adjusted for BMI ( 34021172) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Rapid response to perioperative phenylephrine (change in mean arterial pressure) ( 33168928)
Interacting Genes		23 interacting genes: EWSR1 FXR1 FXR2 GMNN HK1 HPCAL4 LYPLA2 LZTR1 MAGEA12 MAML3 MOB4 PCBD1 PHC1 PHC2 POLR2M RNF2 SFMBT1 SFMBT2 TMEM11 TOB1 TSC1 UBQLN1 UBQLN4	5 interacting genes: APP DKC1 INCA1 MED31 SCMH1
Entrez ID		22955	11313
HPRD ID		11540	07127
Ensembl ID		ENSG00000010803	ENSG00000011009
Uniprot IDs		A0A8Q3SHN2 A0A8Q3SHR9 B3KMZ7 B4DWE6 Q96GD3	A0A140VJC9 O95372
PDB IDs		2P0K	5SYN 6BJE
Enriched GO Terms of Interacting Partners?		PcG Protein Complex PRC1 Complex Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Negative Regulation Of Nucleobase-containing Compound Metabolic Process Sex Chromatin Chromatin Binding Negative Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Metabolic Process Histone Binding Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Transcription Corepressor Activity Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Translation Regulator Activity Negative Regulation Of Biosynthetic Process Nucleus Positive Regulation Of MRNA Catabolic Process Dentate Gyrus Development Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Gene Expression Positive Regulation Of MRNA Metabolic Process Aggresome Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Glucosamine Kinase Activity Memory T Cell Differentiation Negative Regulation Of Macroautophagy Presynaptic Modulation Of Chemical Synaptic Transmission Negative Regulation Of Store-operated Calcium Channel Activity Polyubiquitin Modification-dependent Protein Binding Maintenance Of ER Location Negative Regulation Of Catabolic Process Nucleoplasm Heterochromatin 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Tyrosine Biosynthetic Process Phenylalanine 4-monooxygenase Activity Tyrosine Biosynthetic Process, By Oxidation Of Phenylalanine Perinuclear Region Of Cytoplasm Regulation Of Macroautophagy Regulation Of MRNA Stability Regulation Of RNA Stability	Acetylcholine Receptor Activator Activity Negative Regulation Of Cell Population Proliferation Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Positive Regulation Of Apoptotic Signaling Pathway Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Box H/ACA SnoRNA Binding Protein Localization To Nucleoplasm SnRNA Pseudouridine Synthesis Protein Localization To Cajal Body Box H/ACA Sno(s)RNA Metabolic Process Box H/ACA SnoRNP Complex Box H/ACA Sno(s)RNA 3'-end Processing Enzyme-directed RRNA Pseudouridine Synthesis Box H/ACA ScaRNP Complex Telomerase RNA Stabilization Negative Regulation Of Fibroblast Proliferation Regulation Of Fibroblast Proliferation Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Box H/ACA Telomerase RNP Complex ScaRNA Localization To Cajal Body Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway SnRNA Modification Telomerase Holoenzyme Complex Assembly Regulation Of Primary Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?