LYPLA2

Description		lysophospholipase 2
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Stack Cytosol Extracellular Exosome
	Molecular Function	Phosphatidylcholine Lysophospholipase Activity Protein Binding Palmitoyl-(protein) Hydrolase Activity Hydrolase Activity Cadherin Binding
	Biological Process	Lipid Metabolic Process Fatty Acid Metabolic Process Axon Guidance Acylglycerol Catabolic Process Macromolecule Depalmitoylation Prostaglandin Catabolic Process
Pathways		L1CAM interactions
Drugs
Diseases
GWAS
Novel Interacting Genes		5 novel interacting genes: APP DKC1 INCA1 MED31 SCMH1
Interacting Genes		5 interacting genes: APP DKC1 INCA1 MED31 SCMH1
Entrez ID		11313
HPRD ID		07127
Ensembl ID		ENSG00000011009
Uniprot IDs		A0A140VJC9 O95372
PDB IDs		5SYN 6BJE
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Negative Regulation Of Cell Population Proliferation Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Positive Regulation Of Apoptotic Signaling Pathway Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Box H/ACA SnoRNA Binding Protein Localization To Nucleoplasm SnRNA Pseudouridine Synthesis Protein Localization To Cajal Body Box H/ACA Sno(s)RNA Metabolic Process Box H/ACA SnoRNP Complex Box H/ACA Sno(s)RNA 3'-end Processing Enzyme-directed RRNA Pseudouridine Synthesis Box H/ACA ScaRNP Complex Telomerase RNA Stabilization Negative Regulation Of Fibroblast Proliferation Regulation Of Fibroblast Proliferation Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Box H/ACA Telomerase RNP Complex ScaRNA Localization To Cajal Body Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway SnRNA Modification Telomerase Holoenzyme Complex Assembly Regulation Of Primary Metabolic Process
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