PDZD11 and SIGMAR1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		PDZD11	SIGMAR1
Description		PDZ domain containing 11	sigma non-opioid intracellular receptor 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Adherens Junction Membrane Basolateral Plasma Membrane Pore Complex Anchoring Junction Presynapse	Nucleus Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Cytosol Plasma Membrane Postsynaptic Density Membrane Growth Cone Cytoplasmic Vesicle Cell Projection Synapse Postsynaptic Membrane Anchoring Junction Postsynapse Postsynaptic Density Membrane Glutamatergic Synapse
	Molecular Function	Protein Binding Protein-macromolecule Adaptor Activity	G Protein-coupled Opioid Receptor Activity Protein Binding Signaling Receptor Activity Identical Protein Binding
	Biological Process	Neurotransmitter Secretion Regulation Of Synaptic Assembly At Neuromuscular Junction Pore Complex Assembly Synaptic Vesicle Transport	Lipid Transport Nervous System Development G Protein-coupled Opioid Receptor Signaling Pathway Regulation Of Neuron Apoptotic Process Protein Homotrimerization Regulation Of Postsynapse Assembly
Pathways		Biotin transport and metabolism Vitamin B5 (pantothenate) metabolism Transport of vitamins, nucleosides, and related molecules Ion influx/efflux at host-pathogen interface Ion transport by P-type ATPases	Potential therapeutics for SARS
Drugs			Amitriptyline Remoxipride Haloperidol Dextromethorphan Nortriptyline Fenfluramine Pentazocine Naltrexone Cocaine Hydrocodone Sertraline Dimethyltryptamine Prasterone Phencyclidine Pimavanserin Noscapine Captodiame Pentoxyverine
Diseases
GWAS
Interacting Genes		16 interacting genes: ATP2B2 ATP7A CD79B EDEM1 GDPD2 KIF4A MAGI2 MYO1F NLGN3 RAB11FIP2 SIGMAR1 SMG8 SNX12 TAF1 TEX11 ZMYM3	15 interacting genes: ANK2 DCAF12 DNAJB5 GHSR GNE ITPR3 NFX1 PDZD11 PHF24 RECK RUSC2 SPAG8 SPINK4 SRI VCP
Entrez ID		51248	10280
HPRD ID		06622	03580
Ensembl ID		ENSG00000120509	ENSG00000147955
Uniprot IDs		Q5EBL8	A0A7P0T9D5 A0A7P0Z4C2 B4DR71 Q99720
PDB IDs			5HK1 5HK2 6DJZ 6DK0 6DK1
Enriched GO Terms of Interacting Partners?
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