COPG1 and COPG2

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, cross-linking study, biochemical)
HPRD (in vivo)

		COPG1	COPG2
Description		coat protein complex I subunit gamma 1	coat protein complex I subunit gamma 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Membrane Membrane Coat COPI Vesicle Coat Transport Vesicle COPI-coated Vesicle Membrane Organelle Membrane Cytoplasmic Vesicle	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Membrane Membrane Coat COPI Vesicle Coat Transport Vesicle COPI-coated Vesicle Growth Cone COPI-coated Vesicle Membrane Cytoplasmic Vesicle Bounding Membrane Of Organelle
	Molecular Function	Structural Molecule Activity Protein Binding	Structural Molecule Activity
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Protein Secretion Protein Transport Vesicle-mediated Transport Establishment Of Golgi Localization Organelle Transport Along Microtubule	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Secretion Protein Transport Vesicle-mediated Transport Organelle Transport Along Microtubule
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs		S-(Dimethylarsenic)Cysteine
Diseases
GWAS		Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 26426971 34021172) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	A body shape index ( 34021172) Pancreatic cancer ( 25086665) Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		24 interacting genes: ARCN1 ARF1 CDC42 CFTR COPB1 COPE COPG2 COPZ1 COPZ2 DRD1 FILNC1 H2AX PPBP PTGES3 RAB7A RHOQ RNF10 SACM1L SNCA SUMO2 TAPBP TMED10 WBP2 WEE2-AS1	12 interacting genes: ARCN1 ARL1 COPB1 COPE COPG1 COPZ1 COPZ2 DRD1 HES4 PTGES3 TAPBP TMED10
Entrez ID		22820	26958
HPRD ID		09887	05074
Ensembl ID		ENSG00000181789	ENSG00000158623
Uniprot IDs		Q9Y678	A0A140VK12 Q9UBF2
PDB IDs		1R4X
Enriched GO Terms of Interacting Partners?		COPI Vesicle Coat COPI-coated Vesicle Membrane Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum COPI-coated Vesicle Vesicle-mediated Transport Transport Vesicle Golgi Membrane Intra-Golgi Vesicle-mediated Transport Golgi Vesicle Transport Endoplasmic Reticulum Membrane Establishment Of Localization In Cell Intracellular Protein Transport Intracellular Transport Establishment Of Protein Localization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport Intracellular Protein Localization GBD Domain Binding Cellular Localization Golgi Apparatus Membrane Coat Cytoplasmic Vesicle Organelle Localization Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Transport Glutamatergic Synapse Golgi Localization Golgi-associated Vesicle Membrane Adult Locomotory Behavior Endoplasmic Reticulum-Golgi Intermediate Compartment Synaptic Transmission, Dopaminergic Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Long-term Synaptic Depression Positive Regulation Of Exocytosis Behavioral Response To Cocaine Vesicle-mediated Transport In Synapse Bounding Membrane Of Organelle Secretory Granule Membrane Regulation Of Dopamine Metabolic Process Dopamine Transport Regulation Of Neurotransmitter Uptake Establishment Of Organelle Localization Positive Regulation Of Monoatomic Ion Transmembrane Transport D-glucose Transmembrane Transport Positive Regulation Of Secretion By Cell Positive Regulation Of Filopodium Assembly Monoamine Transport Dopamine Metabolic Process Regulation Of Vesicle-mediated Transport GTPase Activity	COPI Vesicle Coat COPI-coated Vesicle Membrane Transport Vesicle Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Vesicle Transport Intra-Golgi Vesicle-mediated Transport Golgi Membrane COPI-coated Vesicle Intracellular Protein Transport Endoplasmic Reticulum Membrane Protein Transport Vesicle-mediated Transport Intracellular Transport Establishment Of Protein Localization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cellular Localization Establishment Of Localization In Cell Intracellular Protein Localization Cytoplasmic Vesicle Golgi Apparatus Membrane Coat Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Localization Protein Localization To Golgi Apparatus Structural Molecule Activity Cis-Golgi Network MHC Class Ib Protein Complex Assembly Peptide Antigen Stabilization Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Cerebellar Purkinje Cell Layer Maturation Phospholipase D Activator Activity Dopamine Neurotransmitter Receptor Activity, Coupled Via Gs G Protein-coupled Receptor Complex Tapasin-ERp57 Complex Adult Locomotory Behavior Secretory Granule Membrane Conditioned Taste Aversion Sensitization TAP2 Binding TAP Complex Binding Prostaglandin-E Synthase Activity Endoplasmic Reticulum Membrane Habituation Operant Conditioning Unfolded Protein Binding TAP1 Binding
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