FABP3 and TNNI3K

Number of citations of the paper that reports this interaction (PubMedID 12721663)
0

Data Source:
HPRD (two hybrid)

		FABP3	TNNI3K
Description		fatty acid binding protein 3	TNNI3 interacting kinase
Image
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Cytosol Sarcoplasm Extracellular Exosome	Nucleus Cytoplasm
	Molecular Function	Long-chain Fatty Acid Transmembrane Transporter Activity Fatty Acid Binding Protein Binding Cytoskeletal Protein Binding Lipid Binding Long-chain Fatty Acid Binding Icosatetraenoic Acid Binding Oleic Acid Binding	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Fatty Acid Metabolic Process Negative Regulation Of Cell Population Proliferation Response To Xenobiotic Stimulus Long-chain Fatty Acid Transport Intracellular Lipid Transport Response To Insulin Cholesterol Homeostasis Regulation Of Fatty Acid Oxidation Brown Fat Cell Differentiation Phospholipid Homeostasis Response To Fatty Acid Positive Regulation Of Phospholipid Biosynthetic Process Positive Regulation Of Long-chain Fatty Acid Import Into Cell Regulation Of Phosphatidylcholine Biosynthetic Process	Regulation Of Heart Rate Protein Phosphorylation Peptidyl-serine Autophosphorylation Regulation Of Cardiac Muscle Contraction Bundle Of His Cell To Purkinje Myocyte Communication Regulation Of Cardiac Conduction
Pathways		Triglyceride catabolism
Drugs			Fostamatinib
Diseases
GWAS		Alcohol dependence ( 23455491) Body mass index ( 26426971) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)	Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) BMI (adjusted for smoking behaviour) ( 28443625) Body mass index ( 23669352 28892062 26426971 28448500 20935630) Body mass index (age <50) ( 26426971) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Body mass index x age interaction ( 26426971) Body mass index x sex x age interaction (4df test) ( 26426971) Body size at age 10 ( 32376654) Childhood body mass index ( 26604143 33045005) Hip circumference ( 25673412) Menarche (age at onset) ( 27182965 25231870) Mental health study participation (completed survey) ( 31263887) Obesity ( 23563607) Parental longevity (combined parental age at death) ( 29227965) Pubertal anthropometrics ( 23449627) Smoking initiation ( 30617275 33082346) Smoking initiation (ever regular vs never regular) ( 30679032)
Interacting Genes		4 interacting genes: NUP62 SHTN1 TNNI3K VPS28	8 interacting genes: ACTA1 ACTC1 AIP FABP3 FBXO4 HADHB MYBPC3 TNNI3
Entrez ID		2170	51086
HPRD ID		00613	18208
Ensembl ID		ENSG00000121769	ENSG00000116783
Uniprot IDs		A0A384MDY5 P05413	Q59H18
PDB IDs		1G5W 1HMR 1HMS 1HMT 2HMB 3RSW 3WBG 3WVM 3WXQ 4TJZ 4TKB 4TKH 4TKJ 4WBK 5B27 5B28 5B29 5CE4 5HZ9 6AQ1 7EGO 7EUV 7EUW 7FBF 7FBM 7FBN 7FC4 7FCG 7FCX 7FD7 7FDT 7FDU 7FDX 7FEK 7FEU 7FEZ 7FF6 7FFK 7FFX 7FG1 7FG5 7FZQ 7V2G 7V5U 7VB1 7WCI 7WD6 7WDJ 7WE5 7WF0 7WJ1 7WKB 7WKG 7WOM 7WPG 7WPU 7WPW 7WQ7 7X48 7X4J 7X50 7XBC 7XHM 7XHU 8GEW	4YFF 4YFI 6B5J 7MGJ 7MGK
Enriched GO Terms of Interacting Partners?		Ubiquitin Binding Endoplasmic Reticulum Polarization Actin Filament Bundle Retrograde Transport PTB Domain Binding Bundle Of His Cell To Purkinje Myocyte Communication Positive Regulation Of Ubiquitin-dependent Endocytosis Cdc42 Protein Signal Transduction Positive Regulation Of Cellular Component Organization Nuclear Pore Central Transport Channel Positive Regulation Of Mitotic Cytokinetic Process Positive Regulation Of Protein Localization To Centrosome Mitotic Centrosome Separation Peptidyl-serine Autophosphorylation Cytoplasmic Actin-based Contraction Involved In Cell Motility Netrin-activated Signaling Pathway Establishment Of Protein Localization To Organelle Substrate-dependent Cell Migration, Cell Extension Positive Regulation Of Centriole Replication ESCRT I Complex Centrosome Separation Regulation Of Protein Localization To Centrosome Positive Regulation Of Mitotic Cytokinesis Regulation Of Mitotic Cytokinesis Positive Regulation Of Neuron Migration Positive Regulation Of Protein Localization Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway	Sarcomere Myosin Binding Cardiac Muscle Contraction Muscle Contraction Mesenchyme Migration Cardiac Muscle Tissue Morphogenesis Muscle System Process Skeletal Muscle Thin Filament Assembly Muscle Tissue Morphogenesis Cardiac Myofibril Striated Muscle Contraction Actin-myosin Filament Sliding Heart Contraction Heart Process Actin-mediated Cell Contraction Ventricular Cardiac Muscle Tissue Morphogenesis Actin Filament-based Movement Icosatetraenoic Acid Binding C Zone Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions GAF Domain Binding Filopodium Cell Body Regulation Of Cardiac Muscle Contraction Actin Filament Actin Filament-based Process Tissue Morphogenesis Oleic Acid Binding Regulation Of Striated Muscle Contraction Blood Microparticle Actomyosin Structure Organization Positive Regulation Of Long-chain Fatty Acid Import Into Cell Acetyl-CoA C-myristoyltransferase Activity Mitochondrial Fatty Acid Beta-oxidation Multienzyme Complex Regulation Of Muscle Filament Sliding Striated Muscle Myosin Thick Filament Cardiac Troponin Complex Troponin C Binding Cytosol Acetyl-CoA C-acyltransferase Activity Troponin T Binding Cytoplasmic Actin-based Contraction Involved In Cell Motility Long-chain Fatty Acid Binding Regulation Of Phosphatidylcholine Biosynthetic Process System Process Acetyl-CoA C-acetyltransferase Activity (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Regulation Of Muscle Contraction Lamellipodium Enoyl-CoA Hydratase Activity
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