ERG and ETV1

Number of citations of the paper that reports this interaction (PubMedID 9681824)
0

Data Source:
HPRD (in vitro)

		ERG	ETV1
Description		ETS transcription factor ERG	ETS variant transcription factor 1
Image
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Ribonucleoprotein Complex	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Protein Phosphorylation Signal Transduction Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Axon Guidance Muscle Organ Development Mechanosensory Behavior Cell Differentiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Peripheral Nervous System Neuron Development
Pathways
Drugs
Diseases		Prostate cancer Ewing's sarcoma	Prostate cancer Ewing's sarcoma
GWAS		Abdominal aortic aneurysm ( 27899403) Amyotrophic lateral sclerosis (sporadic) ( 24529757) Appendicular lean mass ( 33097823) B-cell acute lymphoblastic leukaemia ( 31767839) B-cell acute lymphoblastic leukaemia (high-hyperdiploidy) ( 31767839) Diastolic blood pressure ( 27841878 30578418) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) General cognitive ability ( 25383866) Granulocyte percentage of myeloid white cells ( 27863252) Gut microbiota relative abundance (Blautia) ( 33208821) Heel bone mineral density ( 30598549 28869591) Hematocrit ( 32888494) Hemoglobin ( 32888494) Iron status biomarkers (iron levels) ( 28334935) Keratinocyte cancer (MTAG) ( 31174203) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 27863252 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels (HVA) ( 23319000) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494 27863252) Multiple sclerosis ( 27386562 31604244) Neonatal lupus ( 20662065) Neutrophil count ( 32888494) Non-response to antidepressants and depression ( 27622933) Platelet count ( 27863252 32888494) Plateletcrit ( 27863252 32888494) Pulse pressure ( 27841878 30578418) Red blood cell count ( 32888494) Refractive error ( 32231278) Response to cognitive-behavioural therapy in anxiety disorder ( 26989097) Sum eosinophil basophil counts ( 27863252) White blood cell count ( 32888494) White blood cell count (basophil) ( 29403010) White blood cell types ( 21738478)	Blond vs. brown/black hair color ( 30531825) Chronotype ( 30696823) Coronary artery disease ( 29212778) Coronary atherosclerosis (time to event) ( 32589924) Extrahepatic cholangiocarcinoma ( 34315874) Height ( 28552196 31217584) Intraocular pressure ( 30591961) Lymphocyte count ( 27863252 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Post bronchodilator FEV1/FVC ratio in smoking ( 30068317) Post bronchodilator percent predicted FEV1 in smoking ( 30068317) Renal underexcretion gout ( 32238385) Triglyceride levels in HIV infection ( 33109212) Type 2 diabetes ( 30718926 32499647 24509480) Verbal declarative memory ( 25648963) White blood cell count ( 32888494)
Interacting Genes		106 interacting genes: ACTB ADAR APP ARK2N ATP5PD CDC5L CLTC COL6A2 CRYAA CSTB DDX21 DDX23 DKC1 DNAJA1 DNAJA2 DNAJA4 EEF1A2 ELAVL1 ETS2 ETV1 EXOSC9 FAM218A FBL FLI1 HERC2 HIPK1 HNRNPA1 HNRNPA2B1 HNRNPAB HNRNPC HNRNPD HNRNPDL HNRNPF HNRNPH1 HNRNPH3 HNRNPU HNRNPUL1 HNRNPUL2 HSPD1 HUWE1 ILF2 ILF3 ITGB2 JUN LANCL1 LARS1 MATR3 MNAT1 MSH3 MYO5A NCL NEUROD2 NFIA NFIB NFIC NOLC1 NONO NPM1 NUMA1 PARP1 PCBP1 PDE9A PIAS1 PIAS3 POLR2A PRKDC PRMT2 PRPF40A PRPF8 PTPRD PUF60 PVT1 RCC2 RING1 RNF111 RNF2 RPLP0 SETDB1 SF3B1 SF3B2 SF3B3 SFPQ SLX4 SMARCE1 SNRNP200 SOX10 SOX6 SPI1 SPOP STUB1 SYN1 TARBP1 TOP1 TOP2B TRIM25 TRIM33 TRIP12 UBR4 UBR5 UHRF1 USP9X WDR13 XRN2 ZBED5 ZBTB44 ZMYM2	20 interacting genes: ATR CCND3 EP300 ERG JUN KAT2B KCNA2 MAPK14 MAPK3 MAPK8 MAPKAPK2 NCOA2 NCOA3 NFE2L2 NSMCE2 PRKACA RPS6KA1 RPS6KA5 SPI1 UBE2I
Entrez ID		2078	2115
HPRD ID		01298	02765
Ensembl ID		ENSG00000157554	ENSG00000006468
Uniprot IDs		A0A0C4DG41 B4DN83 B4DVX5 B5MDW0 P11308	B5MCT2 B7Z2C9 P50549
PDB IDs		1SXE 4IRG 4IRH 4IRI 5YBC 5YBD 6VGE 6VGG	4AVP 4BNC 5ILS
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Metabolic Process Nucleoplasm Nucleus Nucleobase-containing Compound Metabolic Process RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Macromolecule Metabolic Process MRNA Metabolic Process RNA Processing Ribonucleoprotein Complex Macromolecule Metabolic Process Regulation Of Metabolic Process MRNA Processing Regulation Of Primary Metabolic Process RNA Splicing Catalytic Step 2 Spliceosome Spliceosomal Complex Regulation Of Macromolecule Biosynthetic Process Nucleic Acid Binding Regulation Of Gene Expression DNA Metabolic Process DNA Binding Negative Regulation Of Metabolic Process Chromatin Negative Regulation Of Macromolecule Metabolic Process Chromatin Remodeling Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Chromatin Binding Chromatin Organization Regulation Of Telomere Maintenance Via Telomere Lengthening Regulation Of RNA Biosynthetic Process DNA Repair Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA-templated Transcription Alternative MRNA Splicing, Via Spliceosome Nuclear Matrix	Regulation Of Nucleobase-containing Compound Metabolic Process Nucleoplasm Positive Regulation Of Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Protein Serine Kinase Activity Positive Regulation Of Macromolecule Biosynthetic Process Transferase Activity Regulation Of Macromolecule Metabolic Process Intracellular Signal Transduction Positive Regulation Of RNA Metabolic Process Protein Serine/threonine Kinase Activity TORC1 Signaling Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription TOR Signaling Positive Regulation Of Macromolecule Metabolic Process Protein Kinase Activity Nucleus Negative Regulation Of Metabolic Process Regulation Of Gene Expression Kinase Activity Response To Hormone Regulation Of Multicellular Organismal Process Cellular Response To Stress Signal Transduction Cellular Response To Nutrient Levels Protein Modification Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cellular Response To Heat Response To Nutrient Levels MAP Kinase Activity Cellular Senescence Negative Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Component Organization Protein Phosphorylation Positive Regulation Of Cyclase Activity Protein Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Stress-activated MAPK Cascade Response To Mechanical Stimulus
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?